Erythropoiesis in the mouse begins with the production of a distinct population of red blood cells in the blood islands of the visceral yolk sac at day 7.5 postcoitum (p.c.). These primitive yolk sac red blood cells are large (about four times the volume of adult erythrocytes), nucleated and produce a distinctive set of embryonic hemoglobins (Craig and Russell, 1964; Russell and Bernstein, 1966...

p65 is a transcription factor that is involved in many physiological and pathologic processes. Here we report that p65 strongly binds to the miR-23a-27a-24 cluster promoter to up-regulate its expression. As bone marrow-derived cells differentiate into red blood cells in vitro, p65/miR-23a-27a-24 cluster expression increases sharply and then declines before the appearance of red blood cells, sug...

Thirty one term large for gestational age (LGA) infants of non-diabetic mothers were compared with 30 appropriate for gestational age controls. Median absolute nucleated red blood cell counts, lymphocyte counts, and packed cell volumes were significantly higher in the LGA infants than the controls. It is possible that LGA babies of non-diabetic mothers are exposed to relative intrauterine hypoxia.

OBJECTIVES To evaluate the effect of preeclampsia on the cord blood and maternal NRBC count and to correlate NRBC count and neonatal outcome in preeclampsia and control groups. STUDY DESIGN This is a prospective case control observational study. PATIENTS AND METHODS Maternal and cord blood NRBC counts were studied in 50 preeclamptic women and 50 healthy pregnant women. Using automated cell ...