The maintenance of ionic homeostasis in response to changes in the environment is essential for all living cells. Although there are still many important questions concerning the role of the major monovalent cation K(+), cytoplasmic K(+) in bacteria is required for diverse processes. Here, we show that enzyme IIA(Ntr) (EIIA(Ntr)) of the nitrogen-metabolic phosphotransferase system interacts wit...

A novel long-wavelength fluorescence probe has been developed for the detection of nitroreductase (NTR) and hypoxia. could be activated by NTR at 0.1 μM to release the fluorophore and significant changes in fluorescence emission at 658 nm were observed. This feature makes it advantageous for imaging hypoxic cells with minimal endogenous interference.

Oligodendrocytes (OLs) are the primary targets in the autoimmune disease multiple sclerosis (MS). Cell receptors belonging to the tumor necrosis factor receptor (TNF-R) superfamily, such as TNF receptors and fas, are implicated in signaling the injury response of OLs. The p75 neurotrophin receptor (p75(NTR)), another member of the TNF-R superfamily, has been reported to mediate nerve growth fac...

The genomic RNA of different isolates of Citrus tristeza virus (CTV) reveals an unusual pattern of sequence diversity: the 3' halves are highly conserved (homology >90%), while the 5' halves show much more dissimilarity, with the 5' nontranslated region (NTR) containing the highest diversity (homology as low as 42%). Yet, positive-sense sequences of the 5' NTR were predicted to fold into nearly...

Coxsackievirus B3 (CVB3) infections can cause myocarditis in humans and are implicated in the pathogenesis of dilated cardiomyopathy. The natural genetic determinants of cardiovirulence for CVB3 have not been identified, although using strains engineered in the laboratory, cardiovirulence determinants have been identified in the CVB3 5' nontranslated region (5'NTR) and capsid. The myocarditic p...

The p75 neurotrophin receptor (p75NTR) could bind a variety of proteins all with biological significance. While this receptor has no catalytic activities, and therefore influences cellular outcomes through protein-protein interactions, how it controls one cellular event over another remains to be deciphered. Alomone Labs offers a broad range of p75NTR related products, ranging from monoclonal t...

In-depth knowledge about soil moisture dynamics is crucial for irrigation management in precision agriculture. This study evaluates the feasibility of high spatial resolution near-infrared remote sensing with unmanned aerial systems estimation to provide decision support management. A new trapezoid model based on transformed reflectance (NTR) and normalized difference vegetation index (NDVI) in...