نتایج جستجو برای: ns3 helicase

تعداد نتایج: 10524  

Journal: :jundishapur journal of microbiology 0
mohammad-hassan pouriayevali department of virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran taravat bamdad department of virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran; department of virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran. tel: +98-2182884525 mohammad-reza aghasadeghi department of hepatitis and aids, pasteur institute of iran. tehran, ir iran seyed mehdi sadat department of hepatitis and aids, pasteur institute of iran. tehran, ir iran farzaneh sabahi department of virology, faculty of medical sciences, tarbiat modares university, tehran, ir iran

conclusions the pc-ns3 possesses the capacity to express ns3 in the mammalian cell line and demonstrated strong immunogenicity in a murine model. our primary results demonstrated that the immunogenic truncated region of ns3 could be used as a potential vaccine candidate against hepatitis c. results the pcdna3.1 plasmid harboring the coding sequence of ns3 (pc-ns3) was constructed and confirmed ...

Journal: :Journal of virology 2000
N Butkiewicz N Yao W Zhong J Wright-Minogue P Ingravallo R Zhang J Durkin D N Standring B M Baroudy D V Sangar S M Lemon J Y Lau Z Hong

GB virus B (GBV-B) is closely related to hepatitis C virus (HCV) and causes acute hepatitis in tamarins (Saguinus species), making it an attractive surrogate virus for in vivo testing of anti-HCV inhibitors in a small monkey model. It has been reported that the nonstructural protein 3 (NS3) serine protease of GBV-B shares similar substrate specificity with its counterpart in HCV. Authentic prot...

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