Necrotizing enterocolitis (NEC) is a complication of prematurity. The etiology is unknown, but is related to enteral feeding, ischemia, infection, and inflammation. Reactive oxygen species production, most notably superoxide, increases in NEC. NADPH oxidase (NOX) generates superoxide, but its activity in NEC remains unknown. We hypothesize that NOX-derived superoxide production increases in NEC...

NADPH oxidase (Nox) has a dedicated function of generating reactive oxygen species (ROS). Accumulating evidence suggests that Nox has an important role in signal transduction in cellular stress responses. We have reviewed the current evidence showing that the Nox system can be activated by a collection of chemical, physical, and biological cellular stresses. In many circumstances, Nox activatio...

Abstract: Reduction of NOX emissions and fuel consumption are the main topics in engine development, forcing the adoption of complex techniques and components, whose interactions have to be clearly understood for proper and reliable operations and management of the whole system. The investigation presented in this paper aimed at the development of integrated control strategies of turbocharging,...

Diesel vehicles are responsible for most of the traffic-related nitrogen oxide (NOx) emissions, including nitric oxide (NO) and nitrogen dioxide (NO2). The use of after-treatment devices increases the risk of high NO2/NOx emissions from diesel engines. In order to investigate the factors influencing NO2/NOx emissions, an emission experiment was carried out on a high pressure common-rail, turboc...

Tropospheric air pollution has impacts on scales ranging from local to global. Reactive intermediates in the oxidation of mixtures of volatile organic compounds (VOCs) and oxides of nitrogen (NOx) play central roles: the hydroxyl radical (OH), during the day; the nitrate radical (NO3), at night; and ozone (O3), which contributes during the day and night. Halogen atoms can also play a role durin...

Two innovative control technologies for air pollution from the combustion of municipal solid waste (MSW) are discussed. The system concepts of Selective Cat­ alytic Reduction (SCR) and the Electron Beam (E­ Beam) process are presented, along with the extent of demonstrated experience. Estimated capital and op­ erating costs are calculated for each system for oper­ ation on a 1000 tons/day MSW m...

BACKGROUND There have been numerous studies examining the role of nitric oxide (NO) in myocardial ischemia-reperfusion injury; however, few studies have included measurements of NO or related reactive nitrogen species. The purpose of this study was to determine the effects of in vivo regional myocardial ischemia on interstitial fluid (ISF) reactive nitrogen species. METHODS Open chest pigs we...

The Clean Coal Technology (CCT) Demonstration Program is a government and industry co-funded effort to demonstrate a new generation of innovative coal utilization processes in a series of " showcase " facilities built across the country. These projects are carried out on a scale sufficiently large to demonstrate commercial worthiness and to generate data for design, construction, operation, and...

NADPH oxidases (NOX) are reactive oxygen species- (ROS-) generating enzymes regulating numerous redox-dependent signaling pathways. NOX are important regulators of cell differentiation, growth, and proliferation and of mechanisms, important for a wide range of processes from embryonic development, through tissue regeneration to the development and spread of cancer. In this review, we discuss th...