Comorbidity among childhood disruptive behavioral disorders is commonly reported in both epidemiologic and clinical studies. These problems are also associated with early substance use and other markers of behavioral disinhibition. Previous twin research has suggested that much of the covariation between antisocial behavior and alcohol dependence is due to common genetic influences. Similar res...

Richard Owen coined the modern definition of homology in 1843. Owen's conception of homology was pre-evolutionary, nontransformative (homology maintained basic plans or archetypes), and applied to the fully formed structures of animals. I sketch out the transition to an evolutionary approach to homology in which all classes of similarity are interpreted against the single branching tree of life...

Chronic exposure to manganese (Mn) produces a spectrum of cognitive and behavioral deficits associated with a neurodegenerative disorder resembling Parkinson's disease. The effects of high-dose exposure to Mn in occupational cohorts and in adult rodent models of the disease are well described but much less is known about the behavioral and neurochemical effects of Mn in the developing brain. We...

Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats are selected and bred for extreme divergence in two-way active avoidance acquisition. In addition, compared to RLA/Verh rats, RHA/Verh rats are (behaviorally and physiologically) less anxious or reactive to stressors, show increased novelty (sensation)-seeking behavior as well as a higher preference for rewarding substances, and are usu...

OBJECTIVE In an ongoing molecular genetic study of temperament, participants were genotyped to examine the association of smoking with two polymorphisms of the serotonin transporter gene (SERT): the promoter region, 5-HTTLPR, and an intronic variable-number-of-tandem-repeats region (VNTR). METHOD Full information was available for 330 families, and 244 "ever smokers" were identified (54 past ...

The paper reports on the results of the project ‘Evaluating the usage and impact of e-journals in the UK’. Using deep log analysis techniques, we evaluated the use of the Oxford Journals database in regard to life sciences, economics and history by 10 major UK research institutions. The aim of the study was to investigate researchers’ digital behaviour, and to ascertain whether it varied by sub...

Introduction. This study explored graduate students' information behaviour related to their process of inquiry and scholarly activities. Method. In depth, semi-structured interviews were conducted with one hundred graduate students representing all disciplines and departments from Carnegie Mellon University. Analysis. Working in pairs, we coded transcripts of interviews into meaningful categori...

This article argues that existing theory and research on computer-mediated communication (CMC) provide a limited view of information-seeking behavior and proposes a conceptual model for its examination via CMC and new media. Although most CMC environments eliminate or severely reduce nonverbal and contextual information available to address uncertainty, form impressions, and develop relationshi...

The principal task of information professionals is to satisfy the various information needs of users in different contexts, studying their requirements, their seeking habits and their management and use of information. According to information behaviour researchers, information seeking behaviour analysis is the study of the 'activities a person may engage in when identifying their own needs for...