Recent discoveries indicate an important role for ghrelin in drug and alcohol reward and an ability of ghrelin to regulate mesolimbic dopamine activity. The role of dopamine in novelty seeking, and the association between this trait and drug and alcohol abuse, led us to hypothesize that ghrelin may influence novelty seeking behavior. To test this possibility we applied several complementary rod...

Computation and digital processes have become integral to everyday communication. The study of how digital media produce meaning, known as computational semiotics, works towards an understanding of the unique properties and characteristics of communications mediated by computers. Articulating and mapping new forms of communication and expression enabled by digital media is important in understa...

P300 (or P3) is a major positive complex in the human event-related potential, occurring some 300 ms after stimulus onset, and long thought to be the cortical correlate of the Orienting Reflex, our automatic attention-grabbing response to a novel stimulus. The Novelty P3 was the third P3 subcomponent discovered (after P3a and P3b) and appeared promising in its sensitivity to stimulus novelty, t...

Encyclopedia of Structural Health Monitoring. Edited by Christian Boller, Fu-Kuo Chang and Yozo Fujino  2009 John Wiley & Sons, Ltd. ISBN: 978-0-470-05822-0. of possible failure modes, the effects of which on observable (sensor) data are often poorly defined. To compound this, examples of abnormal behavior in high-integrity systems are few and far between; usually, there are insufficient examp...

Service-oriented Web applications allow users to exploit applications over networks and access them from a remote system at the client side, including mobile phones. Individual services are built separately with comprehensive functionalities. In this article, the authors transform a standalone offline novelty mining application into a service-oriented application and allow users to access it ov...

We present a novel approach to online change detection problems when the training sample size is small. The proposed approach is based on estimating the expected information content of a new data point and allows an accurate control of the false positive rate even for small data sets. In the case of the Gaussian distribution, our approach is analytically tractable and closely related to classic...

Managing social-ecological systems can be daunting because of numeric and dynamic complexity. These complexities present great uncertainties for scientists, policy makers, stakeholders, and other groups. When approaching complicated problems, there are often mismatches between problems and solutions. At least three caricatures are useful in demonstrating the mismatch between problem and solutio...