Background: Stenotrophomonas maltophilia (SMA) has emerged as an important pathogen capable of causing opportunistic and nosocomial infection. We performed RNA sequencing (RNA-seq) lung tissues from mice with pulmonary SMA infection over time via aerosolized intratracheal inhalation to investigate transcription profile changes in SMA-infected lungs.

BACKGROUND Extended-Spectrum Beta-Lactamases (ESBLs)-producing bacteria are increasing challenge in the treatment of both community acquired and nosocomial intra-abdominal infections (IAIs). Investigating the characteristics ofpatients with the IAIs caused by ESBL-producing bacteria and assessing the risk factors of ESBLs infection will lead to appropriate therapeutic management. OBJECTIVE To...

The use of extracorporeal membrane oxygenation (ECMO) for adult patients has increased in recent years. A retrospective cohort study of adult patients undergoing ECMO was performed between 19 February 1985 and 10 October 1995 to evaluate nosocomial infections. Seventy-one evaluable patients underwent ECMO for a total of 799 days. Forty-six infections were identified in 32 (45%) of 71 patients. ...

CONTEXT Experts and policy makers have repeatedly called for universal screening at hospital admission to reduce nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection. OBJECTIVE To determine the effect of an early MRSA detection strategy on nosocomial MRSA infection rates in surgical patients. DESIGN, SETTING, AND PATIENTS Prospective, interventional cohort study conducted...

BACKGROUND Although diabetes mellitus is known as a major risk factor for Klebsiella pneumoniae infection, the differences in clinical characteristics between community-acquired and nosocomial K. pneumoniae bacteremia in diabetic patients have been rarely reported. METHODS This retrospective analysis enrolled 193 adult diabetic patients with K. pneumoniae bacteremia hospitalized between Janua...

The nosocomial infection rate within the study period (January 1 December 31, 2010) was highest during January and lowest during December, while it was highest during May and August and lowest during January in 2011. The investigated 170 specimens for nosocomial infection showed that 51.7 and 48.3% had community-acquired and nosocomial infection, respectively. Nosocomial infection included resp...

This study was conducted in PICU of a teaching hospital to estimate the incidence of nosocomial infections, establish the clinical and bacteriological profile and identify probable exogenous source from the environment and personnel. 95 suspected cases of nosocomial infections were studied prospectively, identified as per the guidelines laid down by CDC. The rate of nosocomial infections was 27...