A simple and sensitive method for the simultaneous determination of ethanol, ethyl acetate, tetrahydrofuran, 2-propanol, hexane, dichloromethane and methanol in five drug substances by headspace techniques with FID detection is described. The method was validated for repeatability, linearity, limit of detection, limit of quantification and recovery according to the International Conference on H...

We have established by HPLC age-related reference intervals for sialic acid urinary excretion in 364 control individuals to assist in evaluating the clinical significance of the free sialic acid concentration in urine. In addition, an HPLC method for quantitative analysis of free deoxysialic acid was developed, and age-related reference intervals for excretion of this compound in urine were est...