Cyclo-oxygenase (COX), the enzyme responsible for conversion of arachidonic acid to prostanoids, exists as two isoforms. In most tissues, COX-1 is a constitutive enzyme involved in prostaglandin-mediated physiological processes, whereas COX-2 is thought to be induced by inflammatory stimuli. However, it has previously been reported that COX-2 is the dominant isoform in islets and an insulin-sec...

Cyclooxygenase-2, like the other member of the COX family, COX-1, is a bifunctional enzyme that catalyzes the conversion of arachidonic acid to PGG2 via COX activity and PGG2 to PGH2 via peroxidase activity. PGH2 is the precursor for PGs, prostacyclin, and TXA2. Hence, COX-2 occupies a central position in the biosynthesis of proinflammatory PGE2 and vasoactive prostacyclin and TXA2. COX-2 share...

in order to find the most appropriate planting patter and cultivar of grain corn, an experiment was conducted in agriculture research station of jiroft and kahnooj, iran for two years in 2007 and 2008 as a split-plot experiment based on a randomized complete blocks design with three replications. the main plot was planting patter at four levels of normal planting (single-row on one furrow), dou...

Background: Cyclooxygenase isoforms (COX-1, COX-2) may exert differential regulatory actions on enteric motor functions under normal or pathological conditions. Aims: To examine the occurrence and functions of COX-1 and COX-2 in the neuromuscular compartment of normal distal colon using human and murine tissue. Methods: Gene expression (human, mouse), protein expression (human), gene deletion (...

the waiting time between children births are called tempo. this phenomenon plays a crucial role in the child and mother health. the purpose of the present study is determination of factors which influence this variable of interest. a significance level of 5% and power of 80% considered to calculate the required sample size for this cross sectional study. the sample size of 124 women determined ...

objective: tempo is the average waiting time to next birth for a woman. role of fertility as the most important phenomenon determining population fluctuations due to the studies of it compared with other demographic phenomena be important and review the multifarious socioeconomic factors of it share  a large effective population studies. general purpose of this study is fitting the cox model to...

METHODS Cellular localisation of the cyclooxygenase (COX) isozymes COX-1 and COX-2 was analysed in 24 cholangiocarcinomas, including 17 matched tissues originating from non-tumorous liver tissue adjacent to tumours and seven biopsies of normal human liver, by immunohistochemistry using isozyme selective antibodies. RESULTS In normal liver, constitutive expression of COX-2 protein was a charac...

We propose a mesh comparison method using a new Attribute Deviation Metric (ADM). Considered meshes contain geometric and appearance attributes (material colors, textures, normals,...). The proposed deviation metric computes local differences between attributes of two meshes. Mesh comparison assessment can be done easily and quickly using this metric. We present an application to mesh simplific...

The study of different notions of equivalence is one of the cornerstones of current research in answer-set programming. This is mainly motivated by the needs of program simplification and modular programming, for which ordinary equivalence is insufficient. A recently introduced equivalence notion in this context is hyperequivalence, which includes as special cases strong, uniform, and ordinary ...