Recent developments in engineered timber products, and their availability, durability, renewability, have led to taller more flexible buildings. However, these buildings may experience excessive vibrations, resulting safety serviceability issues due wind or earthquake loads. This paper presents a dynamic analysis of 42-story-tall hybrid-timber building, along with comparative study the performa...

objectives: because of the high rates of accidents, the construction industry has become a hazardous industry in iran and therefore paying more attention is required. this paper investigates safety management in construction companies for improving workers’ safety as one of the ergonomics aims. methods: in order to survey the safety management in construction companies a questionnaire was prepa...

occupational accidents severely deteriorate human capital, and hence negatively affect the productivity andcompetitiveness. but despite these negative points, there are still deficiencies in safety managementperformance and indicators. therefore the safety issue needs an active management. for this reason, thewriter has proposed an approach to evaluate organizations based on safety management. ...

We study entailment of structural and nonstructural recursive subtyping constraints. Constraints are formal inequalities between type expressions, interpreted over an ordered set of possibly infinite labeled trees. The nonstructural ordering on trees is the one introduced by Amadio and Cardelli for subtyping with recursive types. The structural ordering compares only trees with common shape. A ...

INTRODUCTION ............................................................................................................ 1 1.Alphaviruses ....................................................................................................................1 1.1.Alphavirus expression vectors ........................................................................ 1 1.2.Life cycle ...................

UNLABELLED Induction of membrane rearrangements in the cytoplasm of infected cells is a hallmark of positive-strand RNA viruses. These altered membranes serve as scaffolds for the assembly of viral replication factories (RFs). We have recently shown that hepatitis C virus (HCV) infection induces endoplasmic reticulum-derived double-membrane vesicles (DMVs) representing the major constituent of ...

The α and β subunits comprising the hexameric assembly of F1-ATPase share a high degree of structural identity, though low primary identity. Each subunit binds nucleotide in similar pockets, yet only β subunits are catalytically active. Why? We re-examine their internal symmetry axes and observe interesting differences. Dividing each chain into an N-terminal head region, a C-terminal foot regio...

Dengue virus (DENV) causes dengue fever, a major health concern worldwide. We identified an amphipathic helix (AH) in the N-terminal region of the viral nonstructural protein 4A (NS4A). Disruption of its amphipathic nature using mutagenesis reduced homo-oligomerization and abolished viral replication. These data emphasize the significance of NS4A in the life cycle of the dengue virus and demarc...