Skin cancer is the most prevalent and deadliest kind of cancer. Melanoma dangerous type skin cancer, but it can be detected earlier successfully treated. The dermoscopic image classification using Machine Learning (ML) approaches in identifying melanoma increased over last two decades. proposed system involves three stages. Initially, pre-processing employs median filter thresholding approach a...

Background: Solid organ transplant recipients develop cutaneous malignancies at a higher rate and with a more aggressive clinical course when compared to the general population. Due to a lack of current information within the transplant literature, we sought to assess the clinical course, treatment and outcomes of metastatic skin cancer in solid organ transplant recipients. Methods: Medical rec...

background: marjolin's ulcer is a rare, aggressive condition that arises on chronic skin lesions and diseases. in this article, we will report 83 cases of this disease. methods: retrospectively, we retrieved 83 records of patients with cancer arising from chronic skin conditions. data concerning demography, type of original skin insult, time interval between original lesion and cancer, can...

Prognosis of melanoma patients with metastatic disease is very poor. For example, over 95% of melanoma patients with three or more sites of metastatic disease die within 1 year. Treatment failure usually occurs because the drugs used for the treatment of these patients have a low capacity to kill melanoma cells selectively. By using human UACC-62 melanoma cells and human VH-10 skin non-malignan...

Melanoma is the deadliest form of skin cancer and presents a significant health care burden in many countries. In addition to ultraviolet radiation in sunlight, the main causal factor for melanoma, genetic factors also play an important role in melanoma susceptibility. Although genome-wide association studies have identified many single nucleotide polymorphisms associated with melanoma, little ...

Ultraviolet A (UVA) radiation represents more than 90% of the solar UV radiation reaching Earth's surface. Exposure to solar UV radiation is a major risk in the occurrence of non-melanoma skin cancer. Whole genome sequencing data of melanoma tumors recently obtained makes it possible also to definitively associate malignant melanoma with sunlight exposure. Even though UVB has long been establis...

Transplant patients need to be strictly followed, since the immunosuppressive therapies they usually receive can increase the risk of skin complications. This study aims to evaluate the prevalence of neoplastic skin complications in transplant patients. We analyzed 256 liver or kidney transplant patients. The follow-up mean period was 7 ± 3.5 years. The 18.36% of patients developed neoplastic c...

The American Academy of Dermatology (AAD) has designated May as National Melanoma/Skin Cancer Detection and Prevention Month. In 1996, an estimated 1 million cases of skin cancer will be diagnosed, of which approximately 95% will be squamous cell or basal cell carcinomas (1). Although the incidence of melanoma is lower than those of squamous cell and basal cell carcinomas, the case-fatality rat...

Melanoma is the deadliest form of skin cancer and responsible for 4% of all cancer deaths and 86% of skin cancer-related deaths in the United States (Losina et al., 2007). Melanoma is caused by malignant growth of the melanocytes, which are melanin-producing cells found in the skin’s epidermis, hair, and eyes. In melanoma, these cells undergo an uncontrollable cell growth that manifests in the ...