Ionizing radiation is known for its cytotoxic and mutagenic properties. However, recent evidence suggests that chronic sub-lethal irradiation stimulates the growth of melanin-pigmented (melanized) fungi, supporting the hypothesis that interactions between melanin and ionizing photons generate energy useful for fungal growth, and/or regulate growth-promoting genes. There are no quantitative mode...

We present results from a survey for z ∼ 2.85 Lyman-Continuum (LyC) emission in the HS1549+1933 field and place constraints on the amount of ionizing radiation escaping from starforming galaxies. Using a custom narrowband filter (NB3420) tuned to wavelengths just below the Lyman limit at z ≥ 2.82, we probe the LyC spectral region of 49 Lyman break galaxies (LBGs) and 91 Lyα-emitters (LAEs) spec...

Many tumor-targeted strategies have been used worldwide to limit the side effects and improve the effectiveness of therapies, such as chemotherapy, radiotherapy (RT), etc. Biophotonic therapy modalities comprise very promising alternative techniques for cancer treatment with minimal invasiveness and side-effects. These modalities use light e.g., laser irradiation in an extracorporeal or intrave...

We use WR124 (WN8h) and its associated nebula M1–67, to test theoretical non-LTE models for Wolf-Rayet (WR) stars. Lyman continuum ionizing flux distributions derived from a stellar analysis of WR124, are compared with nebular properties via photo-ionization modelling. Our study demonstrates the significant role that line blanketing plays in affecting the Lyman ionizing energy distribution of W...

Background information: Electromagnetic radiation is the transmission of energy in the form of waves having an electric and magnetic component. Almost all forms of electromagnetic radiation, which constitute the electromagnetic spectrum, such as radio waves, visible, infrared, and uliraviolet light, X-rays and gamma rays, are employed in the contemporary Hospital. There are some crucial decisio...

BACKGROUND Melanin, a high-molecular weight pigment that is ubiquitous in nature, protects melanized microorganisms against high doses of ionizing radiation. However, the physics of melanin interaction with ionizing radiation is unknown. METHODOLOGY/PRINCIPAL FINDINGS We rationally designed melanins from either 5-S-cysteinyl-DOPA, L-cysteine/L-DOPA, or L-DOPA with diverse structures as shown ...

Ionizing irradiation is a well‑established therapeutic modality for malignant gliomas. Due to its high cellular uptake, 5‑aminolevulinic acid (ALA) is used for fluorescence‑guided resection of malignant gliomas. We have previously shown that 5‑ALA sensitizes glioma cells to irradiation in vitro. The aim of the present study was to assess whether 5‑ALA acts as a radiosensitizer in experimental g...

OBJECTIVE To assess the non-radiologist physicians' knowledge on the use of ionizing radiation in imaging. MATERIALS AND METHODS Cross-sectional study utilizing an anonymous questionnaire responded by physicians in clinical and surgical specialties, divided into two parts as follows: one including questions about the physicians' characteristics, frequency of imaging studies requests and parti...

Ethanol and ionizing radiation exposure are independently known to cause tissue damage through various mechanisms. The non-enzymatic and enzymatic metabolism of ethanol, the latter via the cytochrome P(450) 2E1-dependent pathway produces free radicals, which deplete cellular glutathione (GSH). Ionizing radiation exposure has been shown to induce lipid peroxidation, DNA damage, protein oxidation...