A second cellulose synthase gene (acsAII) coding for a 175-kDa polypeptide that is similar in size and sequence to the acsAB gene product has been identified in Acetobacter xylinum AY201. Evidence for the presence of this gene was obtained during analysis of A. xylinum mutants in which the acsAB gene was disrupted (I.M. Saxena, K. Kudlicka, K. Okuda, and R.M. Brown, Jr., J. Bacteriol. 176:5735-...

We have previously shown that inducible nitric oxide (iNO)-synthase immunoreactivity is expressed in bronchial epithelium and increased in asthma which suggests a possible role for NO in airway hyperresponsiveness. We tested the hypothesis that exposure of a sensitized animal to antigen could account for the increased expression of iNO-synthase in the airways. We examined the expression of iNO-...

The influence of cyclooxygenase (COX) and NO synthase inhibitors on antinociceptive action of acetaminophen (ACETA) was studied in rats. ACETA increased the nociceptive threshold for both mechanical (Randall-Selitto test) and chemical stimuli (writhing test). In both models the existence of ceiling dose of ACETA was observed. Indomethacin (IND), an inhibitor preferentially acting on COX-1, as w...

The aim of this work is to determine specificities blood pressure (BP) numbers during the day depending on polymorphism A1166C-gene angiotensin II receptor type I and T786C-promoter endothelial NO-synthase gene among residents Ternopil region afflicted with essential arterial hypertension.We have examined 86 patients hypertension who were treated in therapeutic department Central District Hospi...

objective(s): nitric oxide (no), a product of inducible nitric oxide synthase (inos), contributes in germ cell apoptosis. this study was aimed to evaluate the effects of aloe vera gel (avg) on male wistar rat reproductive organ, serum no level, and expression of inos gene in leydig cells. materials and methods:adult male wistar rats (n=36) were used for experiments in three groups. the experime...