Abnormality in glucose tolerance appears to correlate with arteriosclerotic disease, even when the abnormality is quite mild. Though there is no evidence for prevention of these vascular problems by correction of the carbohydrate abnormality, it seems reasonable to attempt such a correction in an investigational setting. We have used sulfonylurea (tolbutamide, chlorpropamide) in children and yo...

Brain-computer interfaces (BCIs) are now feasible for use as an alternative control option for those with severe motor impairments. The P300 component of the evoked potential has proven useful as a control signal. Individuals do not need to be trained to produce the signal, and it is fairly stable and has a large evoked potential. Even with recent signal classification advances, on-line experim...

quantum information, secret sharing, quantum cryptography, quantum computation We investigate the concept of quantum secret sharing, where a secret quantum state is distributed between n parties in such a way that certain subsets of the parties can jointly recover the secret, while other subsets of the parties can acquire absolutely no information about it. In a ((k,n)) threshold scheme, any su...

Targeted gene correction employs a site-specific DNA lesion to promote homologous recombination that eliminates mutation in a disease gene of interest. The double-strand break typically used to initiate correction can also result in genomic instability if deleterious repair occurs rather than gene correction, possibly compromising the safety of targeted gene correction. Here we show that single...

BACKGROUND The recording of human movement is an essential requirement for biomechanical, clinical, and occupational analysis, allowing assessment of postural variation, occupational risks, and preventive programs in physical therapy and rehabilitation. The flexible electrogoniometer (EGM), considered a reliable and accurate device, is used for dynamic recordings of different joints. Despite th...

Central pontine myelinolysis (CPM), a neurologic disorder caused most frequently by rapid correction of hyponatremia, is characterized by demyelination that affects the central portion of the base of the pons. There are no inflammatory changes, and blood vessels are normal. Clinical features usually reflect damage to the descending motor tracts and include spastic tetraparesis, pseudobulbar par...

Focal dome osteotomy (FDO) allows deformity correction without secondary translational deformity. The purpose of this study was to evaluate the degree of correction and knee functional outcome after correction of frontal knee deformity using femoral supracondylar FDO fixed with plate and screws. A prospective study included 12 consecutive cases of femoral frontal plane deformity that underwent ...