Transcriptional networks, regulated by extracellular signals, control cell fate decisions and determine the size and composition of developing tissues. One example is the network controlling bipotent neuromesodermal progenitors (NMPs) that fuel embryo elongation by generating spinal cord and trunk mesoderm tissue. Here, we use single-cell transcriptomics to identify the molecular signature of N...

Improvement on the stability and loading of unfunctionalized single wall carbon nanotubes (SWNTs) in amide solvents is necessary to enhance the performances of SWNT-polymer composites used for optical applications (e.g., as non-linear saturable absorbers). We show that polyvinylpyrrolidone (PVP) can not only increase the stability of ultrasonically dispersed HiPco SWNTs in pure N-methyl-2pyrrol...

The Pentaneand Toluene-Soluble Fractions of a Petroleum Residue and three Coal Tars by Size Exclusion Chromatography and UV-Fluorescence Spectroscopy — A petroleum atmospheric pressure distillate residue and three tars derived from different coals using different severities of thermal treatment were separated into seven fractions using column chromatography on silica and sequential elution by t...

Nicotinamide riboside kinase (NRK) has an important role in the biosynthesis of NAD(+) as well as the activation of tiazofurin and other NR analogs for anticancer therapy. NRK belongs to the deoxynucleoside kinase and nucleoside monophosphate (NMP) kinase superfamily, although the degree of sequence conservation is very low. We report here the crystal structures of human NRK1 in a binary comple...

Self-stabilization provides non-masking fault tolerance in distributed systems. Self-stabilizing algorithms (SSA) are defined on the assumption that either the system’s topology is fixed over time or topology changes are isolated events occurring at a very low rate. These assumptions are not valid in wireless sensor networks (WSNs) where link qualities change rapidly. Therefore, neighborhood ma...

five new aromatic poly(amide-imide)s (5a-e) were synthesized by direct polycondensationreaction of n-(4-carboxy phenyl) trimellitimide (3) with five aromatic diamines (4a-e) by usingtriphenyl phosphite in n-methyl-2-pyrrolidone (nmp) and pyridine at solution containingdissolved cacl2. all of the polymers were obtained in quantitative yields with inherentviscosities between 0.29-0.40 dl/g. the r...

A neoplasia maligna de próstata (NMP) é a segunda mais incidente no sexo masculino Brasil, representando 29,2% todos os casos novos em 2020, perdendo apenas para o câncer pele não-melanoma. faixa etária acometida 50 70 anos idade, com incidência maior países desenvolvidos. O objetivo deste trabalho analisar número internações e óbitos por NMP adultos 20 69 anos, período 2012 2021, na região Nor...

The Nominal Mapping Parameter (Chierchia 1998) has been proposed as a semantic parameter to account for the cross-linguistic distribution of bare nominals. We examine specific predictions that the NMP makes with respect to the bare singular arguments and bare singular predicates. Brazilian Portuguese allows bare singulars in argument position while English and other Romance languages doe not. F...

We have found that bromo(triphenylphosphine)copper(I), an air-stable and soluble copper(I) complex, can be used as a catalyst in the synthesis of diaryl ethers. Using this catalyst, we have synthesized diaryl ethers from electron-rich aryl bromides and electron-rich phenols in the presence of cesium carbonate, in 17–24 h, in NMP. We also found that electron-deficient aryl bromides couple with p...