نتایج جستجو برای: nitrosourea

تعداد نتایج: 1960  

2014
Giuseppe Lombardi Patrizia Farina Alessandro Della Puppa Diego Cecchin Ardi Pambuku Luisa Bellu Vittorina Zagonel

Fotemustine is a third-generation nitrosourea showing efficacy in various types of tumors such as melanoma and glioma. We reviewed the most important studies on fotemustine treatment in glioma patients analyzing its pharmacological profile and its activity and safety. Fotemustine was used as single agent or in association with new targeted drugs such as bevacizumab; fotemustine was used both as...

Journal: :Indian Journal of Pharmaceutical Education and Research 2022

Abstract: Intranasal drug delivery is a promising route for directly to the brain acute or chronic treatments. A direct offers rapid approach delivering drugs central nervous system without using parenteral route. Carmustine nitrosourea used treat tumors, multiple myeloma, lymphoma, and Hodgkin’s disease but its use limited by very little half-life in body fluids. The nanoparticles have shown g...

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