نتایج جستجو برای: nitazoxanide

تعداد نتایج: 375  

Journal: :Nature chemical biology 2018
Yi Qu Jan Roger Olsen Xing Yuan Phil F Cheng Mitchell P Levesque Karl A Brokstad Paul S Hoffman Anne Margrete Oyan Weidong Zhang Karl-Henning Kalland Xisong Ke

Wnt (wingless)/β-catenin signaling is critical for tumor progression and is frequently activated in colorectal cancer as a result of the mutation of adenomatous polyposis coli (APC); however, therapeutic agents targeting this pathway for clinical use are lacking. Here we report that nitazoxanide (NTZ), a clinically approved antiparasitic drug, efficiently inhibits Wnt signaling independent of A...

Journal: :Journal of Genetic Engineering and Biotechnology 2020

2014
Jeff Basile M. Stanley Branch Svetang V. Desai Christopher Arnold Alastair Smith Tzu-Hao Lee

A 43-year-old woman presented with recurring upper abdominal pain. She had a 5-year history of symptomatic cholelithiasis without improvement following cholecystectomy. She had no prior history of elevated liver tests or jaundice. Her travel history was pertinent for annual trips to the Bahamas. On admission, the patient had a bilirubin of 4.7 mg/dL and liver enzymes more than 5 times the upper...

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