Urease activation is critical to the virulence of many human and animal pathogens. Urease possesses multiple, nickel-containing active sites, and UreE, the only nickel-binding protein among the urease accessory proteins, activates urease by transporting nickel ions. We performed NMR experiments to investigate the solution structure and the nickel-binding properties of Bacillus pasteurii (Bp) Ur...

Autophagy is an intracellular recycling and degradation process for regulating tumor progression, survival and drug resistance. Nickel compounds have been identified as human carcinogens. However, the role of nickel-induced autophagy in lung carcinogenesis has not yet been fully elucidated. In this study, we determined that hexokinase 2 (HK2), which phosphorylates glucose and regulates autophag...

Hydrogenases are generally classified as iron-sulfur-containing proteins with four to twelve iron atoms in different cluster arrangements. Through physiological, chemical and spectroscopic studies,nickel has also been found to be a constitutive metal of several hydrogenases and shown to be involved in a redox linked process. The [NiFe] hydropnnses are now the most intensivelly studied nickel en...

Nickel is a ubiquitous trace element and it occurs in soil, water, air and of the biosphere. It is mostly used to manufacture stainless steel. Nickel is the commonest cause of metal allergy. Nickel allergy is a chronic and recurring skin problem; females are affected more commonly than males. Nickel allergy may develop at any age. Once developed, it tends to persist life-long. Nickel is present...

Nickel is released to the atmosphere by windblown dust, volcanoes, combustion of fuel oil, municipal incineration, and industries involved in nickel refining, steel production, and other nickel alloy production. The form of nickel emitted to the atmosphere is dependent upon the source. Complex nickel oxides, nickel sulfate, and metallic nickel are associated with combustion, incineration, and s...

Nickel is a ubiquitous trace element and the commonest cause of metal allergy among the people. Nickel allergy is a chronic, recurring problem; females are affected more commonly than males. Nickel allergy may develop at any age. Once developed, it tends to persist life-long. Nickel is present in most of the dietary items and food is considered to be a major source of nickel exposure for the ge...

Metal ion homeostasis is critical to the survival of all cells. Regulation of nickel concentrations in Escherichia coli is mediated by the NikR repressor via nickel-induced transcriptional repression of the nickel ABC-type transporter, NikABCDE. Here, we report two crystal structures of nickel-activated E. coli NikR, the isolated repressor at 2.1 A resolution and in a complex with its operator ...

Potential applications of nickel nanoparticles demand the synthesis of self-protected nickel nanoparticles by different synthesis techniques. A novel and simple technique for the synthesis of self-protected nickel nanoparticles is realized by the inter-matrix synthesis of nickel nanoparticles by cation exchange reduction in two types of resins. Two different polymer templates namely strongly ac...

~HE pmcess of beta-disintegration can be considered as a four-particle pmcess, i.e., a process in which four particles are created simultaneously. Thus, e.g. , the process leading to the emission of an electron can be considered as the creation of a proton, a neutrino, Rnd an electron in positive energy states, and of a neutron in a negative state. is known in nickel but it has been assigned' t...

Zinc-Nickel electrodeposits have been widely adopted for surface treatment of automobile steel sheet for high corrosion resistance. In this work the effect of pulse parameters on the Zn-Ni alloy electrodeposits was investigated. The hardness, thickness, corrosion resistance and composition of deposits thus produced were investigated. The surface topography of the deposits was also observed in S...