Background: CXCL13 has been implicated in the formation of ectopic germinal centers (GC) minor salivary gland (MSG) inflammatory lesions SS patients. Recent studies suggest that serum levels associate with disease severity and risk for non-Hodgkin’s lymphoma (NHL) development. Objectives: To validate clinical utility by investigating potential associations saliva various histopathologic (includ...

Adult Non-Hodgkin’s Lymphoma (NHL) is a diverse group of lymphoid malignancies, with an increasing annual trend world over. NHL has shGwn an increase by 39% in Caucasians and 46% in black population and is at least three times more frequent than Hodgkin’s disease, as shown by the SEER study.Intermediate grade lymphoma still constitutes the largest proportion of NHL. Increased incidenceof NHL is...

Targeted radioimmunotherapy in non-Hodgkin's B-cell lymphoma (NHL) offers an efficacious therapy and minimal toxicity compared to conventional chemotherapy. Iodine 131 tositumomab ((131)I-TST) is a murine monoclonal antibody against the CD20 cell surface protein and is directly covalently conjugated to (131)I, a radioactive beta and gamma emitter. While initially approved for use in relapsed, r...

Primary non-Hodgkin's lymphoma (NHL) of the gastrointestinal tract is the most common extranodal NHL and accounts for 4%-20% of all NHL . Mantle cell lymphoma (MCL) comprises 2.5%-7% of all NHL . Gastrointestinal tract involvement occurred in 20% of MCL, which is commonly manifested as numerous, small, spherical, or hemispherical polyps, termed multiple lymphomatous polyposis (MLP). Hereby we r...

Hepatitis C virus (HCV) is one of the main viral causes of hepatocellular carcinoma (HCC) and is associated with lymphoproliferative disorder such as non-Hodgkin's lymphoma (NHL). However, there are only few case reports on concomitantly induced NHL and HCC by HCV. Herein, we report a case of synchronous NHL and HCC in a patient with chronic hepatitis C which was unexpectedly diagnosed during l...

Environmental exposure has been linked to non-Hodgkin's lymphoma (NHL). Toxic volatile compounds were found in groundwater downstream of an industrial site in southern Israel. The risk of NHL and clinical characteristics of NHL patients were analyzed in relation to their proximity to the site.

The incidence of non-Hodgkin’s lymphomas (NHLs) has increased for the past 30 years among men and women of all ages (1). A number of epidemiologic studies have been undertaken to determine the causes of this increase. In several studies (2–5), prior history of blood transfusion has been associated with an increased risk of NHL. This increased risk has been attributed to the immunosuppressive ef...

By April 1995, 302 cases of vertically acquired HIV infection had been reported through the British Paediatric Association Surveillance Unit. Over 50% of these children had developed an AIDS indicator disease, including nine malignancies (seven cases of non-Hodgkin's lymphoma (NHL) and two of Kaposi's sarcoma). There were two other malignancies that were not AIDS indicator diseases. In children...

BACKGROUND Non-Hodgkin lymphoma (NHL) is the most common AIDS-related malignancy in developed countries. An elevated risk of developing NHL persists among HIV-infected individuals in comparison to the general population despite the advent of effective antiretroviral therapy. The mechanisms underlying the development of AIDS-related NHL (A-NHL) are not fully understood, but likely involve persis...