Newcastle disease (ND) is a highly contagious, severe disease of poultry caused by pathogenic strains of Newcastle disease virus (NDV; or avian paramyxovirus-1). NDV is endemic in wild birds worldwide and one of the economically most important poultry pathogens. Most of the published strains are outbreak-associated strains, while the apathogenic NDV strains that occur in wild birds, posing a co...

Crohn's disease (CD) is an inflammatory disease of the gastrointestinal tract (GIT) tract and can affect several parts of the digestive system. There is a relationship between impaired mucosal barrier in the GIT of inflammatory bowel disease patients and the role of bacteria such as Mycobacterium avium paratuberculosis in CD. Apart from different therapeutic approaches for treating CD, developm...

Foot-and-mouth disease (FMD) is a contagious viral disease of livestock with significant economic effect. It is prevalent in various regions of Asia, Africa, and South America. The causative agent of this disease is called foot-and-mouth disease virus (FMDV), which is a member of Aphthovirus genus. Vaccination is an effective technique to prevent the complications of FMD and to eradicate the di...

Newcastle disease virus (NDV) infects most avian species. The serious consequence is the disease (frequently fatal) that occurs when virulent strains of the virus infect domestic chickens. The epidemiology of Newcastle disease (ND) in commercial chickens is fairly well understood. Infected chickens are the usual source of virus, which can be transported mechanically by fomites or by people. Pre...

Newcastle disease (ND) is one of the most devastating poultry infections because of its worldwide distribution and accompanying economical threat. In the present study, we characterized the ND virus (NDV) K148/08 strain from wild mallard duck, with regard to safety, thermostability, immunogenicity, and protective efficacy against velogenic ND viral infection. The NDV K148/08 strain offered enha...

Newcastle disease virus (NDV) can cause severe disease in chickens. Although NDV vaccines exist, there are frequent reports of outbreaks in vaccinated chickens. During 2009-2010, despite intense vaccination, NDV caused major outbreaks among commercial poultry farms in Indonesia. These outbreaks raised concern regarding the protective immunity of current vaccines against circulating virulent str...

Viral infections, including Newcastle disease (ND), constitute a major health problem in the rapidly growing poultry industry of Nepal. Despite regular vaccination commercial farms, ND virus (NDV) outbreaks are frequently reported raising concern over safety and immunogenicity live-attenuated vaccines being used. This study was performed to compare four commercially available Nepal after admini...

<p><strong>Background.</strong> Traditionally, poultry is kept and reared by women in extensive production systems. In Kenya most developing countries, smallholder productivity constrained diseases such as Newcastle disease (ND), which preventable via a vaccine, yet contributes to significant morbidity mortality among flocks primarily owned managed villages. <strong>Obje...