It has been recognized that the antibacterial sera produced by the immunization of the horse and the rabbit with Type I pneumococci, although possessing type specificity, exhibit marked differences in certain immunological properties. The distinctive characteristics of the two sera have interested numerous investigators, but as yet there is almost no evidence to indicate what constituents of th...

Two established international reference preparations (IRP) for thromboplastins, i.e. RBT/90 (rabbit, plain) and rTF/95 (recombinant human, plain) have been calibrated against each other in a 7-centre exercise performed in 2000. The purpose of the study was to compare the calibration results with those of the original calibration study performed in 1995. The international sensitivity index (ISI)...

BACKGROUND In this pilot feasibility study, we aimed to establish a reproducible means of performing serial optical coherence tomography (OCT) procedures in the abdominal aorta of the cholesterol-fed rabbit. METHODS Eight cholesterol-fed New Zealand White rabbits were assigned to abdominal aortic balloon injury at baseline (n=6) or as controls (n=2). Three of the balloon injured rabbits recei...

The presence of autoantibodies in New Zealand Black (NZB) mice suggests a B cell tolerance defect however the nature of this defect is unknown. To determine whether defects in B cell anergy contribute to the autoimmune phenotype in NZB mice, soluble hen egg lysozyme (sHEL) and anti-HEL Ig transgenes were bred onto the NZB background to generate double transgenic (dTg) mice. NZB dTg mice had ele...

The rabbit (Oryctolagus cuniculus) is an important experimental animal for studying human diseases, such as hypercholesterolemia and atherosclerosis. Despite this, genetic information and RNA expression profiling of laboratory rabbits are lacking. Here, we characterized the whole-genome variants of three breeds of the most popular experimental rabbits, New Zealand White (NZW), Japanese White (J...

Postweaning data on 643 rabbits from 122 litters representing four breed types, New Zealand White (NZW) and Californian (CAL) purebreds, CAL X NZW (CXN), and Flemish Giant (FG) crossbreds (the latter group was a collection of FG X CAL, FG X Champagne D'Argent [CHA], and 1/2 FG X 1/4 CAL X 1/4 CHA), were gathered over five seasons and compared for growth, feed efficiency, and survival-related pe...

The guanylation of tRNA in a cell-free system has been achieved in a lysate of rabbit reticulocytes. The enzymatic nature of the reaction is indicated by sensitivity to trypsin, heat inactivation, and by the precipitation of the guanylating activity with ammonium sulfate. The lysate did not incorporate guanine after endogenous tRNA was removed by RNase, or by binding the tRNA to an anion exchan...

The development and progression of systemic lupus erythematosus is mediated by the complex interaction of genetic and environmental factors. To decipher the genetics that contribute to pathogenesis and the production of pathogenic autoantibodies, our lab has focused on the generation of congenic lupus-prone mice derived from the New Zealand Black (NZB) strain. Previous work has shown that an NZ...

Objective to examine the effect of Bevacizumab injection angiogenesis which amount and density blood vessel as indicators after trabeculectomy procedure. Method This was a true experimental study using 16 eyes New Zealand White Rabbit eye treated by procedure with eight control group Balanced Saline Solution (BSS) treatment Bevacizumab. It injected subconjuctiva trabeculectomy. At end all rabbi...