Journal:
:iranian journal of basic medical sciences
0
bahram letafat department of chemistry, central tehran-branch, islamic azad university, tehran, iran
raheleh shakeri institute of biochemistry and biophysics, university of tehran, tehran, iran
saeed emami department of medicinal chemistry and pharmaceutical sciences research center, faculty of pharmacy, mazandaran university of medical sciences, sari, iran
saeedeh noushini department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran
negar mohammadhosseini department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran
nayyereh shirkavand department of chemistry, central tehran-branch, islamic azad university, tehran, iran
objective(s): chalcones and their rigid analogues represent an important class of small molecules having anticancer activities. therefore, in this study the synthesis and cytotoxic activity of new 3-benzylidenchroman-4-ones were described as rigid chalcone analogues. materials and methods: the reaction of resorcinol with 3-chloropropionic acid in the presence of cf3so3h was afforded correspon...
