Folliculitis Decalvans (FD) is a form of inflammatory scarring alopecia; its causative mechanism is not well understood. It affects both sexes, may start in adolescence or adulthood and occurs more commonly in African Americans compared to Caucasians [1]. Staphylococcus aureus can be isolated from the pustules in most cases, but whether this is a primary or secondary process is unknown. It has ...

Frontal fibrosing alopecia (FFA) is the most common cicatricial alopecia, whose prevalence has greatly increased, mainly in post-menopausal women, results from irreversible epithelial hair follicle (HF) stem cell (eHFSC) damage. Exposure to ingredients commonly found personal care products might trigger FFA-related immune responses. In fact, 76.2% of patients with FFA and/or LPP show type IV se...

We describe the case of a 45-year-old man who presented with a 5-month history of unilateral pruritic linear erythematous papules and atrophy on the chin and mandibular area. Dermoscopy showed areas of cicatricial alopecia with absence of follicular openings, perifollicular erythema and pigment. Lichen planopilaris of the face is a rare variant with only 13 cases reported in the literature. © 2...

CONTEXT Central centrifugal cicatricial alopecia (CCCA; originally entitled follicular degeneration syndrome, or hot comb alopecia) was first described in African American women utilizing hot combs and/or strong chemical hair care products. CASE REPORT A 67 year old African American female was evaluated for the presence of alopecic areas occurring on the scalp vertex, and spreading centrifuga...

A 10 year old boy presented to our hospital with nephrotic syndrome relapse and signs of steroid toxicity in the form of posterior capsular cataract, affection of linear growth and stage 2 hypertension, in addition to steroid induced adiposity and fungal infection of the scalp resulting in cicatricial alopecia. He was diagnosed as nephrotic syndrome 6 months back. He went into remission with st...

cGVHD: chronic graft-vs-host disease HSCT: hematopoietic stem cell transplant INTRODUCTION Pili torti is a term that originates from Latin (pili meaning hair, torti meaning twisted) used to describe the irregularly flattened and twisted appearance of hair shafts on microscopic hair mount evaluation. Clinically, affected patients have fragile, coarse, and sparse hair. The 1808 rotation along the...

Acanthosis nigricans – an ill-defined, velvety, hyperpigmented plaque involving the fold of the skin, including the axilla, neck and groin Atrichia – absence of hair Atrophoderma – atrophy of the skin Blepharitis – inflammation of the eyelids Cicatricial alopecia – scarring alopecia Copy number variations – DNA segments with 1 kb or more of gains or losses Corneodesmosin – a protein found in co...

Primary cicatricial alopecias (PCA) are a diverse group of inflammatory hair disorders of unknown aetiology, clinically characterised by the loss of hair shafts, visible follicular ostia, and variable degrees of scalp inflammation. The hair follicle is the primary target of the disease process and persistent inflammation leads to irreversible damage to the hair follicle’s stem cells. Ultimately...

BACKGROUND Classic lichen planopilaris (LPP) is a patchy form of primary lymphocytic cicatricial alopecia localized on the vertex of the scalp. It is important, however, to be aware of other, less recognized presentations that may be missed without dermatoscopy and pathology. METHODS AND RESULTS We report 26 patients with LPP presenting with subtle erythema and scaling colocalized in the area...