The effect of VSV infection in rabbit eye was investigated. The findings indicated that maximum virus growth in the rabbit cornea coincided with peak keratitis on postinfection day 1. Thereafter, keratitis was generally not observed, whereas infectious virus was detected in the cornea through day 6. Primary virus infection in the cornea of one eye produced serum-neutralizing antibody which did ...

EDITORIAL SYNOPSIS Because all the parameters needed to calculate an adequate dose of antacid for patients with peptic ulcer will probably never be known before treatment, a mathematical method is presented of calculating the minimum dose using the data of various authors as regards gastric secretion and emptying. Also studied is the effect of antacids on secretion rate and emptying time. It wa...

Background Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants are increasingly observed in vaccinated individuals. Immune responses towards SARS-CoV-2 variants, particularly Omicron-BA.5, poorly understood. We investigated the humoral and cellular immune of hospitalized COVID-19 patients during Delta Omicron infection waves. Methods The correspond...

The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November 2021 South Africa and Botswana, as well a sample from traveller Hong Kong1,2. Since then, has been detected globally. This appears to be at least infectious Delta (B.1.617.2), already caused superspreader events3, outcompeted within weeks several countries metropo...

The envelope (Env) glycoprotein of human immunodeficiency virus type 1 (HIV-1) is the major target of neutralizing antibody responses and is likely to be a critical component of an effective vaccine against AIDS. Although monomeric HIV envelope subunit vaccines (gp120) have induced high-titer antibody responses and neutralizing antibodies against laboratory-adapted HIV-1 strains, they have fail...

Rabbit antibody capable of neutralizing the pressor activity of the enzyme renin, derived from hog kidneys, was characterized with respect to type and capacity to react serologically. Three antirenin antibodies were detected, both a precipitating and nonprecipitating, neutralizing antibody as well as a neutralizing antibody capable of being absorbed by inactivated renin. The precipitating, neut...

Maximilian Larena, Natalie A Prow, Roy A Hall, Nikolai Petrovsky and 6 Mario Lobigs 7 8 1 Department of Emerging Pathogens and Vaccines, John Curtin School of Medical 9 Research, The Australian National University, Canberra, Australia 10 2 Australian Infectious Diseases Research Centre, School of Chemistry and Molecular 11 Biosciences, The University of Queensland, St Lucia, Australia 12 3 Vaxi...

Neutralizing antibodies against fowl tumor agents can be produced in rabbits by injection of heavy materials obtained from chicken tumor. Similar sediments from normal chicken spleen produce no neutralizing antibodies. The complement-fixing antibodies produced by both materials are unrelated to the neutralizing antibodies.