نتایج جستجو برای: neutralization
تعداد نتایج: 12636 فیلتر نتایج به سال:
Fourteen cytopathic bovine rotaviruses isolated from naturally affected calves were characterized serologically by serum neutralization. Antisera were prepared in guinea pigs against the three isolates and the Lincoln strain of bovine rotavirus. These four rotaviruses were segregated into at least two distinct serotypes (designated types 1 and 2) by serum neutralization. The remaining 11 isolat...
We have examined the relationship between coreceptor utilization and sensitivity to neutralization in a primary isolate of human immunodeficiency virus type 1 and its T-cell line-adapted (TCLA) derivative. We determined that adaptation of the primary-isolate (PI) virus 168P results in the loss of the unique capacity of PI viruses to utilize the CCR5 coreceptor and in the acquisition by the TCLA...
Antibodies that neutralize autologous transmitted/founder (TF) HIV occur in most HIV-infected individuals and can evolve to neutralization breadth. Autologous neutralizing antibodies (nAbs) against neutralization-resistant (Tier-2) viruses are rarely induced by vaccination. Whereas broadly neutralizing antibody (bnAb)-HIV-Envelope structures have been defined, the structures of autologous nAbs ...
Cryo-EM reveals the molecular basis of SARS-CoV-2 cross-neutralization by monoclonal antibody 47D11.
Abstract Feminist linguistic activism has gained prominence among Western feminists as a way to eliminate sexism in language and everyday life. In Russian, gender specification (known feminitivy ) represents the mainstream approach practiced by grassroots feminist reformers. However, alternative approaches aimed at neutralization proliferate. The paper examines prospects challenges of both writ...
An enzyme-linked immunosorbent assay was developed to detect antibodies to infectious bovine rhinotracheitis virus in bovine sera. The test used viral antigen purified in a sucrose density gradient, and the antibody titers detected were up to 100 times higher than those seen in the serum neutralization test. When 250 sera were tested by those two tests, 146 were positive and 49 were negative in...
A seed lot of strain SF 1684 of rhinovirus type 2 prepared in human embryonic lung cells (WI-38) contained aggregates which interfered with its neutralization by homotypic or homologous antisera. The same virus showed no evidence of aggregation at five other passage levels studied. Virus in the seed lot was not identified correctly, and the titer of homologous antiserum was mistakenly considere...
The global market for antibody-based drugs is expected to double within a decade given their clinical success against diseases where conventional therapies fail. Our studies of antibody structure and function have revealed subtle differences in the role of VH and VL domains in antigen recognition and virus neutralization functions. Studies of bovine antibody fragments, such as, scFv (single cha...
This paper tests the hypothesis Licensing by Cue (Steriade 1997) applying it to the distribution of Russian plain-palatalized contrast in coronal stops /t/ vs. /t/ in two environments (V_C, V_#). The hypothesis holds that the maintenance of the contrast should correspond to more acoustic information in the signal and higher identification rate, and that its neutralization should be accompanied ...
A radioimmunological neutralization assay for the determination of hepatitis B e antibody is described. The method is compared with a blocking and a competitive assay and with immunodiffusion. The neutralization assay proved to be the most sensitive method, and results obtained by this method were reproduced most easily. The frequency of nonspecific results may be up to 1% of the sera tested. A...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید