Isolated human red blood cell membrane fragments (RBCMF) were found to take up Ca(++) in the presence of ATP.(1) This ATP-dependent Ca(++) uptake by RBCMF appears to be the manifestation of an active Ca(++) transport mechanism in the red cell membrane reported previously (Schatzmann, 1966; Lee and Shin, 1969). The influences of altering experimental conditions on Ca(++)-stimulated Mg(++) ATPase...

The embryotoxic potential of the commonly used fungicide, methyl 2-benzimidazolecarbamate (MBC) was evaluated in rat and hamster embryo limb bud (LB) and midbrain (CNS) cell micromass cultures. Cultures were exposed to seven concentrations of 0.03, 0.12, 0.49, 1.95, 7.81, 31.25 and 125 μg MBC/ml. Developmental toxicity was assessed via the following parameters: cytotoxicity, by quantifying neut...

Cytotoxicity of resorcinol to 3T3 fibroblast in short- (3 hrs) and long-term (72 hrs or 6 weeks) exposure was investigated. The effects of resorcinol on cell viability (neutral red uptake, NRU assay), mitochondrial function (MTT assay) and total cell protein (Kenacid Blue assay) were estimated. As a model for long-term exposure an INTEGRA CL 6-WELL bioreactor was used. The concentrations of res...