The DNA sequences of genomes from G + C-rich and A + T-rich lymphotropic herpesviruses [i.e. gammaherpesviruses; Epstein-Barr virus and herpesvirus saimiri (HVS)] are deficient in CpG dinucleotides and contain an excess of TpG and CpA dinucleotides relative to frequencies predicted from their mononucleotide compositions. In contrast, for sequences from genomes of G + C-rich and A + T-rich neuro...

CC-BY-NC 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. Abstract Recombinant Sindbis viruses are important tools in neuroscience because they combine rapid and high transgene expression with large payloads. Currently, two packaging systems are available for making neurotropic virus, but both prod...

Although influenza is primarily a respiratory disease, it has been shown, in some cases, to induce encephalitis, including people acutely infected with the pandemic A/California/04/2009 (CA/09) H1N1 virus. Based on previous studies showing that the highly pathogenic avian influenza (HPAI) A/Vietnam/1203/2004 H5N1 virus was neurotropic, induced CNS inflammation and a transient parkinsonism, we e...

The purpose of this research wanted to know about the influence opinion leader towards belief level foreign brand, especially neurotropic vitamin. data was gained from 186 responden by questionnaires and interview. Sampling method used non probability sampling purposive technique select respondents engaging health care professionals including nurse, midwife general practicioners. Simple regress...

The article presents the results of studying pharmacokinetics and enzymatic stability a new pharmacologically active compound GZK-111– N-phenylacetyl-glycyl-L-proline ethyl ether in comparison with noopept – N-phenylacetyl-L-prolyl-glycine rats. It has been shown that both compounds are intensively metabolized body experimental animals, while one main metabolites is cyclo-L-prolylglycine (CPG),...