In this paper, we present a paradigm for alleviating the challenge of fiber tracking through edematous brain regions. This new framework of fiber tracking is applied to the brain tumor datasets 1, 2 and 3 provided as part of the 3 MICCAI DTI Tractography Challenge. Although the data was single shell, b = 1000s/mm, we were able to successfully fit a two-compartment model to the data and extracte...

Glioma is the most common intra-axial brain tumor characterized by invasion into the surrounding white matter (WM) tracts. These tumors are usually diagnosed by conventional MRI, but this method is unable to describe the relationship between tumor and neighboring WM tracts. Diffusion tensor tractography (DTT) is a new imaging modality which can solve this problem. The current study evaluated th...

Cushing and other great neurosurgeons made their mental preparations for surgical procedures through extensive, beautiful drawings. Three-dimensional visualization was in those days supported through interpretation of pneumoencephalograms with displacements of structures indicating where a space-occupying process might be located. Today this visualization necessary for each neurosurgeon is part...

Radical resection of a pathological lesion along with the preservation of eloquent cerebral tissue is the principle goal of neurosurgery. Brain lesions are usually diagnosed by conventional magnetic resonance imaging (MRI), but this method is unable to describe the relationship between lesions and neighboring specific white matter (WM) tracts. Diffusion tensor tractograghy (DTT) is a new sophis...

OBJECTIVES Previous research exploring the patient experience of awake craniotomy (AC) has yielded contrasting accounts. The current study aimed to explore the lived experience of having undergone an AC in the United Kingdom. DESIGN This was a qualitative, semi-structured interview study. Interviews were audio-recorded and transcribed verbatim. Data were analysed using interpretative phenomen...