A 58-year-old man developed subacute gait instability, oscillopsia, and vertigo. Examination showed ataxia periodic alternating nystagmus (PAN) (video). MRI revealed T2 hyperintensities in the left cerebellum nodulus (figure). CSF was inflammatory. Autoantibody evaluation positive for Kelch-like protein 11 (KLHL11) serum by tissue-based immunofluorescence assay cell-based assay, prompting ident...

Neurologic symptoms and neurodegeneration are important causes of morbidity and mortality in man. Although many pathogenic mechanisms could account for neurologic dysfunction, considerable interest has focused on a group of neurotoxins known as the ‘excitotoxins’. Quinolinic acid (QUIN) is an excitotoxic L-tryptophan and kynurenine pathway metabolite that is an agonist of N-methyl-uaspartate (N...

To test the hypothesis that cortisol levels reflect the extent of neurologic dysfunction and predict patient outcome, neurologic function and cortisol levels were determined in 120 traumatically brain injured patients who never received glucocorticoid treatment. Their mean age was 29 years and 78% were men. The impact of intoxication was examined in 59 patients who had ethanol levels measured. ...

BACKGROUND The neuroprotective properties of xenon may improve cerebral outcome after cardiac surgery using cardiopulmonary bypass (CPB). However, its disposition to expand gaseous bubbles that during CPB present as cerebral air emboli (CAE) could abolish any beneficial effect or even worsen cerebral outcome. Therefore, the authors studied the impact of xenon on neurologic, cognitive, and histo...

OBJECTIVES Inflammatory response is discussed as a contributor to neurologic deficits following cardiac surgery using deep hypothermic circulatory arrest (DHCA). Nuclear Factor Kappa B (NFkappaB) presents a central transcription factor whose expression pattern and subsequent role very much depend on the type and manner of cerebral injury. This study was designed to assess the time course of cer...

To clinically and radiologically report a traumatic spinal epidural hematoma (SEH) that completely resolved, without surgical treatment. A 17-year-old woman presented with back pain, lower motor weakness, and sensory change after trauma to the lower back area. Neurologic examination revealed paraparesis (grade 3/5) and radiating pain in both legs at the L5 dermatome. Magnetic resonance imaging ...

how to cite this article:   dalirani r, mahyar a, ayazi p, ahmadi gh. neurological manifestations of renal diseases in children in qazvin/ iran. iran j child neurol. summer 2016; 10(3):24-27 . abstract objective renal diseases are one of the most common causes of referrals and admissions of children, hence it is important to know their neurological presentations. this study aimed to determine n...

Idiopathic normal pressure hydrocephalus (iNPH) is the most common cause of hydrocephalus in adults. The diagnosis may be challenging, requiring collaborative efforts between different specialists. According to the International Society for Hydrocephalus and Cerebrospinal Fluid Disorders, iNPH should be considered in the differential of any unexplained gait failure with insidious onset. Recogni...

INTRODUCTION Laryngeal dysfunction may be divided into three categories; organic, neurologic and functional disorders. Dysphonia and hoarseness are the most common symptoms and, in some cases, the only signs of laryngeal dysfunction. In differential diagnosis of any type of chronic hoarseness, a neoplastic process must be considered and, thus continuous light video laryngoscopy can provide impo...