A case of colchicine-induced rhabdomyolysis is reported. The 72-year-old man was hospitalized because of poor appetite, fatigue, myalgia, and leg weakness, shortly after starting treatment with colchicine for 5 months. Laboratory results revealed serum creatine kinase: 3627 IU/L, creatinine: 2.3 mg/dL, myoglobin: 1160.5 ng/mL (reference range: male: 17.4-105.7 ng/mL, female: 14.3-65.8 ng/mL) an...

Although measurements of nerve conduction velocity in man were first made nearly a hundred years ago, the procedure was not used clinically until 1948 when Hodes, Larrabee, and German reported reduced conduction velocity in regenerating motor nerves. Later, Hodes (1949) described slow conduction in surviving nerve fibres after poliomyelitis, and more recently it has been shown that conduction m...

Carpal tunnel syndrome (CTS) is the most well-known and frequent form of median nerve entrapment, and accounts for 90% of all entrapment neuropathies. Entrapment neuropathies of the ulnar nerve are relatively common with ulnar neuropathy at the elbow more prevalent than ulnar neuropathy at the wrist. The diagnosis of ulnar neuropathy at the elbow is usually confirmed in a relatively straight – ...

OBJECTIVE The authors’ laboratory has previously demonstrated beneficial effects of noninvasive low intensity focused ultrasound (liFUS), targeted at the dorsal root ganglion (DRG), for reducing allodynia in rodent neuropathic pain models. However, rats DRG is 5 mm below skin when approached laterally, while humans typically 5–8 cm deep. Here, using a modified liFUS probe, authors feasibility e...

Rabbit tibial nerves were subjected to direct, acute graded compression by means of an inflatable compression chamber. The acute and long term effects of 50, 200 and 400 mmHg applied for two hours on nerve function and nerve fibre structure were investigated. A pressure of 50 mmHg applied for two hours induced only minimal or no acute deterioration of maximal conduction velocity and nerve fibre...

Objectives When the nerve is injured near its entrance to the muscle belly, we cannot perform conventional methods. One useful method in such a situation is neurotization surgery. In this study, Bone marrow mesenchymal stem cells (BMSCs) implanted into the paralyzed muscle after neurotization surgery. These cells can stimulate axon growth and motor endplate formation, also prevent muscle atroph...

Sixteen autogenous sural nerve grafts used for ulnar and median injuries in the forearm have been studied neurophysiologically up to two and a half years after operation. Motor and sensory nerve conduction studies revealed a slow but sustained improvement during the follow-up period. By two years, motor conduction velocity across the graft itself reached in most cases 40 to 85% of the conductio...

Acute Flaccid Myelitis (AFM), a polio-like paralysis in children no older than 21, has recently reemerged and increasing numbers of such cases have been reported worldwide since 2012. Accurate and early diagnosis of this condition could help with better management of the disease. A 9- year- old girl with chief complaint of headache, fever and vomiting was subsequently affected by an acute...

Hopf's technique was used to measure motor nerve conduction velocity of fibres in the deep peroneal nerve in clinical conditions where damage to the peripheral nervous system was probable. A particular distribution of motor nerve fibre conduction velocity was shown by the analysis of the findings in some of the groups investigated, illustrating the advantages of this method as compared with rou...

RESULTS — In addition to an effect of duration of diabetes and A1C, which were both associated with low nerve conduction velocity and response amplitude, we found that the presence of nephropathy, retinopathy, or a clinical diagnosis of neuropathy was associated with low nerve conduction velocity and amplitude. In the case of nonproliferative retinopathy, the odds ratio (OR) for being in lowest...