Neuromuscular blocking agents (NMB) are now routinely used to facilitate tracheal intubation, mechanical ventilation and skeletal muscle relaxation throughout the entire surgical procedures. Murphy et al reported that residual paralysis resulting from inadequate reversal is an important contributing factor to critical postoperative respiratory events (inadequate pulmonary functions, reduced pha...

The incidence and severity of muscle pain was assessed in 150 males who underwent bronchoscopy using thiopentone and suxamethonium iodide or chloride for anaesthesia. In 50 patients tubocurarine 3-5 mg, diplacin 10-15 mg or kvalidil 10-15 mg was injected intravenously after the induction dose of thiopentone. In a further group of 50 patients neostigmine 0.5-0.75 mg was injected intramuscularly ...

background: we aimed to compare clinical effects of sugammadex versus combination of anticholinergic-anticholinesterase agents for reversing of nondepolarizing neuromuscular block in pediatric patients.materials and methods: a total of 60 pediatric patients  whom should be performed general anesthesia in the supine position were enrolled to this randomized double-blinded clinical trial.fentanyl...

In unanaesthetized patients atropine and neostigmine in doses normally used by anaesthetists to reverse muscle relaxants produced a pronounced increase in bowel activity. This response occurred whether atropine was given before or simultaneously with neostigmine.The response still occurred in 38% of patients anaesthetized without halothane, and possibly this increase in motility might endanger ...

Congenital myasthenia gravis is caused by genetic mutations affecting neuromuscular transmission, characterized by muscle weakness usually starting in childhood. A two and a half years old male child presented with bilateral ptosis and hoarseness of voice. The symptoms progressed giving the clinical impression of congenital myasthenia gravis. A series of tests were done including Ice Pack Test,...