Objective: To study the determinants and outcome of prelabour rupture of membrane at term pregnancy in Patan Hospital. Method: A prospective, hospital based case control study done in maternity ward of Patan Hospital over the period of three months (Poush 2059-Phalgun 2059). A total no of 100 pregnant women with prelabor rupture of membrane and 100 pregnant women without prelabor rupture of mem...

Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) infect a large proportion of the world's population. Infection is life-long and can cause periodic mucocutaneous symptoms, but it only rarely causes life-threatening disease among immunocompetent children and adults. However, when HSV infection occurs during the neonatal period, viral replication is poorly controlled and a large proportion ...

Epidemiologic studies have demonstrated that some bacteria colonization or infections in early-life increased the risk for subsequent asthma development. However, little is known about the mechanisms by which early-life bacterial infection increases this risk. The aim of this study was to investigate the effect of neonatal Streptococcus pneumoniae infection on the development of adulthood asthm...

One of the Millennium Development Goals (MDG-4) is to reduce child mortality by up to two-thirds by 2015. In most developing countries, a higher proportion of neonatal deaths are observed. We quantify the causes of neonatal morbidity and mortality at a rural hospital. A retrospective review of consecutive neonatal admissions to Empangeni Hospital, between January and December 2005, was conducte...

BACKGROUND Neonatal herpes is a rare but potentially devastating condition with an estimated 60% fatality rate without treatment. Transmission usually occurs during delivery from mothers with herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) genital infection. However, the global burden has never been quantified to our knowledge. We developed a novel methodology for burden estimation and pr...

conclusions in the present study, we identified a key gene rps16 and a significant module involved in ribosome biogenesis in eukaryotes that were related to neonatal sepsis, which might be potential biomarkers for early detection and therapy for neonatal sepsis. background the exact interacting factor that response to the infection for neonatal sepsis is still needed to urgently to be disclosed...

Citation: Simanek AM, Uddin M, Yolken RH and Aiello AE (2016) Use of Archived Neonatal Bloodspots for Examining Associations between Prenatal Exposure to Potentially Traumatic or Stressful Life Events, Maternal Herpesvirus Infection and Lifetime History of Generalized Anxiety Disorder in Offspring. Front. Environ. Sci. 4:54. doi: 10.3389/fenvs.2016.00054 Use of Archived Neonatal Bloodspots for ...

  Introduction :Jaundice is the most common cause of hospitalization of infants in the first month of life. Delivery and maternal and neonatal risk factors may affect the progression of complications of jaundice. This study aimed to investigate the problems of pregnancy and delivery in neonates with jaundice. Methods: This descriptive study was performed on 2796 full term 3 to 29 day infants w...

Background Neonatal sepsis is one of the major causes of neonatal morbidity and mortality globally. Its incidence varies from 1 to 4 cases per 1,000 live births in developed countries. The burden of the problem occurs in the developing world while most confirmation is derived from developed countries. This study is aimed to assess the prevalence of neonatal sepsi...