herpes simplex virus (hsv) is a worldwide contagious infection disease.  it usually transmitted during childhood via nonsexual contacts. one of the important causes of genital herpes in developed countries is hsvi. having knowledge about distribution and prevalence of this infection in pregnant women may help to choose an appropriate treatment and prevention methods. 65 pregnant women who have ...

Background and Aims: Herpes simplex virus (HSV) is responsible for several significant human viral diseases, with severity ranging from subclinical to fatal infection. Herpes simplex virus type 2 (HSV2) infections are more commonly seen in association with the genitalia and surrounding areas, and can be transmitted to newborns during childbirth. Generalized infections in newborns are also predo...

conclusions the results of this study show that the incidence of nosocomial infection in neonates is high and decreasing the risk factors such as prematurity, mechanical ventilation and reducing invasive procedures can decrease the infection and improve rapid recovery in these neonates. patients and methods this cross-sectional retrospective study was performed during an 18- month period (2012 ...

statement of the problem: alveolar bone necrosis induced by herpes zoster infection is considered as a rare manifestation of osteomyelitis and few case reports are presented in the literature. purpose: the aim of this study was to evaluate mandibular osteomyelitis caused by herpes zoster in the immunocompromised patients with histopathologically documented osteomyelitis in the mandible and herp...

introduction: hyperbilirubinemia is a relatively common disorder among infants in iran. bacterial infection and jaundice may be associated with higher morbidity. previous studies have reported that jaundice may be one of the signs of infection. the aim of this study was to determine the incidence rate, presentation time, severity of jaundice, signs and complications of infection within neonatal...

The prophylactic and therapeutic efficacy of interleukin-12 was studied by using murine models of herpes simplex virus infection. Prophylactic administration consisted of two intraperitoneal doses of interleukin-12 given 48 and 24 h prior to infection. Therapeutic intraperitoneal administration of interleukin-12 commenced 6 h after the mice were infected with herpes simplex virus and was contin...

Herpes simplex virus type 1 is an important epithelial pathogen and has the potential for significant morbidity in humans. Here we demonstrate that a cell surface scavenger receptor, macrophage receptor with collagenous structure (MARCO), previously thought to enhance antiviral defense by enabling nucleic acid recognition, is usurped by herpes simplex virus type 1 and functions together with he...