AIM The aim of this study was to identify the personality traits of alcohol and human immunodeficiency virus (HIV)-positive patients and to compare them with normal controls. MATERIALS AND METHODS This cross-sectional study included 100 consecutive patients with alcohol dependence and HIV each and a control group of 100 normal cases without any physical or psychiatric illness. A score of 2 or...

Recently, we characterized neoamphimedine (neo) as an ATP-competitive inhibitor of the ATPase domain of human Topoisomerase IIα. Thus far, neo is the only pyridoacridine with this mechanism of action. One limiting factor in the development of neo as a therapeutic agent has been access to sufficient amounts of material for biological testing. Although there are two reported syntheses of neo, bot...

In three studies, a General Factor of Personality (GFP) was found to occupy the apex of the hierarchical structure. In Study 1, a GFP emerged independent of method variance and accounted for 54% of the reliable variance in a multitrait-multimethod assessment of 391 Italian high school students that used self-, teacher-, and parent-ratings on the Big Five Questionnaire - Children. In Study 2, a ...

Over 5000 senior managers attending a structured assessment centre completed three tests (Revised NEO Personality Inventory, NEO-FFI; the Myers Briggs Type Indicators, MBTI; the Fundamental Interpersonal Relations Orientation, FIRO-B). Given their rank and responsibilities they were categorised as Non-Managers or specialists, Middle Managers and Senior Managers (Manager of Managers or Leaders)....

Although there has been substantial debate and research concerning the economic impact of neo-liberal practices, there is a paucity of research about the potential relation between neo-liberal economic practices and population health. We assessed the extent to which neo-liberal policies and practices are associated with population health at the national level. We collected data on 119 countries...

Temperaments are often regarded as biologically based psychological tendencies with intrinsic paths of development. It is argued that this definition applies to the personality traits of the five-factor model. Evidence for the endogenous nature of traits is summarized from studies of behavior genetics, parent-child relations, personality structure, animal personality, and the longitudinal stabi...

Presently the conventional structure of personality, the Five-Factor Model (FFM), has faced criticism for inadequately capturing the full range of existing traits, particularly those reflecting antisocial behavior. The FFM has also not received sufficient application of genetically informed analyses to its extraction and validation. We explored these criticisms, and carried out four behavioral ...