Necrotizing scleritis is an immune-mediated ocular inflammatory process, characterized by an area of avascular necrosis and a profound inflammation of the sclera and episclera. Necrotizing scleritis and its association with peripheral ulcerative keratitis--necrotizing sclerokeratitis (NS)--represents a serious threat for vision and eye integrity, evolves very fast if untreated, and its finding ...

Streptococcus spp are common opportunistic pathogens of mammals and are associated with a variety of diseases affecting multiple organ systems. Necrotizing fasciitis is a severe, debilitating disease in adult dogs that can result in systemic illness and death. Toxic shock– like syndrome, a typically fatal sequel of necrotizing fasciitis in dogs. In dogs, S. canis is the most common streptococca...

BACKGROUND Recently, necrotizing fasciitis has been reported in patients treated with bevacizumab, usually secondary to wound healing complications, gastrointestinal perforations, or fistula formation. The risk of invasive Haemophilus influenzae type b infection is significantly increased in immunocompromised hosts. However, necrotizing fasciitis due to Haemophilus influenzae type b in a patien...

PURPOSE To evaluate the clinical features, associated factors, and treatment outcomes of scleritis in the Korean population. METHODS Medical records were retrospectively reviewed for 94 eyes of 76 patients with scleritis. Clinical features of scleritis, including systemic disease, presence of microorganisms, serologic markers, history of previous ocular surgery, and use of immunosuppressants ...

Necrotizing infundibular crystalline folliculitis is a rare condition characterized by folliculocentric waxy papules in the seborrheic areas of adult patients, with intrafollicular filamentous birefringent deposits as histopathologic clue. Although real pathogenesis necrotizing remains unclear, material seems to be derived from an interaction between such superficial microorganisms gram-positiv...

Cervical necrotizing fasciitis is a fulminant infection that spreads along the fascial planes, causing subcutaneous tissue death characterized by rapid progression and systemic toxicity. Dental infection is the most common nidus of cervical necrotizing fasciitis. Streptococcus and Staphylococcus species are found to be the most commonly isolated organisms in many bacteriological analyses of cer...

PURPOSE Prophylactic antibiotics have been used in acute necrotizing pancreatitis with mixed results. This meta-analysis analyzes the effects of prophylactic antibiotics in necrotizing pancreatitis. METHODS Multiple databases and abstracts were searched for randomized trials comparing treatment with prophylactic antibiotics to treatment without prophylactic antibiotics in necrotizing pancreat...