OBJECTIVE To compare specific characteristics and clinical outcomes of monomicrobial necrotizing fasciitis caused by Aeromonashydrophila and Klebsiella pneumoniae. MATERIAL AND METHODS Cases of monomicrobial necrotizing fasciitis caused by A. hydrophila (n = 11) and K. pneumoniae (n = 7) over an 8-year period were retrospectively reviewed. Differences in mortality, patient characteristics, cl...

The optimal management of necrotizing pancreatitis continues to evolve. Currently, conservative intensive care treatment represents the primary therapy of acute severe necrotizing pancreatitis, aiming at prevention of organ failure. Following this mode of treatment most patients with sterile necroses can be managed successfully. Surgery might be considered as an option in the late phase of the ...

Figure 1. (a) Left medial thigh showing discoloration and swelling. Maximal pain to palpation was in the centrally marked area, but pain could be elicited as far back as the dotted lines. (b) Left medial thigh following surgical debridement down to viable fat, fascia, and muscle. DESCRIPTION A 28-year-old woman with a raised body mass index presented feeling unwell with a 16-hour history of inc...

Necrotizing fasciitis is an uncommon but life-threatening infection primarily involving the superficial fascia. Note the blue-gray color change of the vulvar skin lateral to areas of ulceration (A), The superficial fascia of the vulva is in continuity with that of the anterior abdominal wall. This incision reveals normal-appearing subcutaneous tissue in its superior aspect compared to the dull ...

Early recognition and treatment of necrotizing fasciitis (NF) is essential for survival. Idiopathic NF occurs in the absence of a known causative factor or portal of entry for bacteria, so it may not be considered immediately when patients are admitted. This study aimed to identify specific features of idiopathic NF that are important for early recognition and to assess factors associated with ...

BACKGROUND Renal involvement in rheumatoid arthritis (RA) is common and has a negative impact on patient survival. Only few cases have been reported of necrotizing glomerulonephritis (GN) associated with myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) in patients with RA. CASE PRESENTATION We report a patient with RA who developed a necrotizing GN associated with ANCA-MPO, tre...

In this article, we present the first case of necrotizing fasciitis affecting the abdominal wall caused by Serratia marcescens and share results of a focused review of S. marcescens induced necrotizing fasciitis. Our patient underwent aorto-femoral bypass grafting for advanced peripheral vascular disease and presented 3 weeks postoperatively with pain, erythema and discharge from the incision s...

Varicella is usually considered to be a benign disease in healthy children; however, serious complications can occur such as necrotizing fasciitis and toxic shock syndrome. We describe a 38-month-old girl with necrotizing fasciitis and streptococcal toxic shock syndrome following varicella. She was previously healthy and vaccinated against varicella at 12 months of age. She had been diagnosed w...

Necrotizing sialometaplasia usually heals within 4 to 10 weeks with conservative treatment, and rarely recurs. When necrotizing sialometaplasia is present on the hard palate it may occur unilaterally or bilaterally. In this case, necrotizing ulceration occurred on the left hard palate of a 36-year-old woman after root canal treatment of the upper left first premolar under local anesthesia. Afte...

Necrotizing fasciitis, a near-fatal soft-tissue infection complicating obstetric operative wounds, is a rare entity in obstetrics. Herein, we report two cases of necrotizing fasciitis in severely undernourished and anemic women following obstetric operative procedures. Both undernourishment and anemia compounded the already existing immune-suppressed state in pregnancy and may have lead to life...