Human granulocyte-macrophage colony-stimulating factor (GM-CSF) enhances numerous functions of mature neutrophils (PMN) including phagocytosis, superoxide responses to chemotaxins, antibody-dependent cellular cytotoxicity, and expression of complement receptors. A central question concerns whether the mechanism of enhancement involves quantitative increases in the response of all cells v subpop...

background: occurrence of resistance against antibioticsand inadequate efficacy of some vaccines necessitates studies ofnatural immunostimulators in aquaculture. shrimps shell derivedfrom chitosan can be used as immune stimulators in fish.objectives: in this study, the effects of oral administration ofchitosan, derived from shrimp shell, on some immune responsesand disease resistance in cyprinu...

Chronic granulomatous disease (CGD) is characterized by recurrent infections, and is usually associated with a complete inability of phagocytic cells to generate superoxide anion (O2-). Rarely, variant forms of CGD have been reported in which there is reduced, but detectable, O2- production by phagocytic cells. We describe three adult males in two kindreds with a unique form of X-linked cytochr...

BACKGROUND: Occurrence of resistance against antibioticsand inadequate efficacy of some vaccines necessitates studies ofnatural immunostimulators in aquaculture. Shrimps shell derivedfrom Chitosan can be used as immune stimulators in fish.OBJECTIVES: In this study, the effects of oral administration ofchitosan, derived from shrimp shell, on some immune responsesand disease resistance in Cyprinu...

The local symmetry of (1-x)Na0.5Bi0.5TiO3-xKNbO3 (NBT-xKN, x = 0.01−0.07) ceramics was thoroughly examined using high-energy synchrotron x-ray scattering and analysed the pair distribution function (PDF) method. At room temperature, structure NBT-xKN (x best refined monoclinic C1c1 structures within local-range (r<22 Å) rhombohedral R3c medium-range (22 Å <r <52 Å). Furthermore, exists from tem...

Received: Revised: Accepted: 2014–06–19 2014–07–08 2014–07–08 The dynamics of innate and specific immunity was investigated in dogs under halothane general anaesthesia and lumbosacral epidural anaesthesia using lidocaine. Phagocytic number (PN), phagocytic index (PI), and nitro blue tetrazolium (NBT) test were used to determine phagocytic properties of neutrophils during both anaesthesia regime...

Acute promyelocytic leukemia (APL) is an interesting model for cancer research because of the presence of the specific PML-RARalpha fusion gene associated with the clinical response to retinoic acid differentiation therapy. To better understand and improve differentiation induction with retinoic acid, we have established a human APL-ascites model in SCID mice using the NB4 human APL cell line. ...

Innate immune responses are useful to determine the health status of fish and to evaluate the effect of immunomodulatory substances in fish farming. Leukocytes respiratory burst was measured in pacu (Piaractus mesopotamicus) using chemiluminescence assay and nitroblue tetrazolium (NBT) reduction assay. The nitroblue tetrazolium reduction seemed more adequate than chemiluminescence assay for leu...

PURPOSE To assess the safety and usefulness of neutron brachytherapy (NBT) as an adjuvant in the treatment of patients with gastroesophageal junction adenocarcinoma (GEJAC) with external beam radiation (EBRT), with or without chemotherapy. METHODS AND MATERIALS In total, 197 patients with localized, advanced GEJAC received EBRT and NBT with or without chemotherapy. Radiotherapy consisted of e...