Recent studies have shown that aprepitant, a substance – P/ Nk 1 receptor antagonist is effective in postoperative vomiting. The present study was designed to find out whether addition of aprepitant to ondansetron would be more effective than ondansetron alone in prevention of post operative nausea and vomiting in patients undergoing laparoscopic surgeries. After obtaining informed consent, 50 ...

OBJECTIVE To study if acupuncture, combined with ondansetron treatment, reduces nausea and vomiting associated with cyclophosphamide infusion in patients with rheumatic diseases. METHODS Thirty-nine patients were treated with acupuncture at point PC 6 and/or in the ear to decrease nausea and vomiting. The patients reported the severity of nausea and number of bouts of vomiting at the start of...

Postoperative nausea and vomiting is common after cardiac surgery and may contribute to significant morbidity. Gastric decompression during anesthesia has been used for postoperative nausea and vomiting prophylaxis in shorter duration noncardiac surgery with conflicting results. We tested the hypothesis that gastric decompression during elective coronary revascularization surgery with cardiopul...

BACKGROUND Nausea and vomiting in early pregnancy are troublesome symptoms for some women. We undertook a single blind randomized controlled trial to determine whether acupuncture reduced nausea, dry retching, and vomiting, and improved the health status of women in pregnancy. METHODS The trial was undertaken at a maternity teaching hospital in Adelaide, Australia, where 593 women less than 1...

A prospective trial was performed to better assess the risk of nausea and vomiting and the rescue value of tropisetron (TRO), a 5-HT3 receptor antagonist, in 88 patients undergoing fractionated radiotherapy to the abdomen or to large supradiaphragmatic fields and failing a first anti-emetic trial with metoclopramide (MET). Nausea was graded 0 (absent), 1 (mild), 2 (moderate) and 3 (severe). Nau...

Cisplatin is an effective chemotherapeutics against a wide range of cancers. However, it causes significant nausea and vomiting which limit its usefulness. In the present study, the effects of methanolic root extract of Pluchea lanceolata (DC.) C. B. Clarke , asteraceae ( MPL ) was investigated against cisplatin-induced nausea using a rat pica model. In rat pica model, rats react to cispla...