background and objective: nitric oxide (no) plays a role in thermoregulation and growth of protozoa. this work aimed to add the molecule no in physiology of protozoa in contact with abused narcotic substances. materials and methods: a sedative drug, morphine, was infused into a cell chamber containing paramecia . the cell response to the drug was recorded promptly after drug infusion using a po...

BACKGROUND Prisoner's addiction is one of the major problems in many countries which imposes very high medical costs and social harm to communities. This study investigated the pattern of substance use and related factors in male prisoners in one of the prisons in southeastern Iran. METHODS This cross-sectional study was carried out in 2016. The study population was inmates of a prison in sou...

UNLABELLED WHAT IS KNOWN ON THE SUBJECT?: Novel psychoactive substances (NPS) include synthetic drugs mimicking the effects of illicit drugs, e.g. synthetic cannabinoids, and herbs such as Salvia divinorum. NPS are substances that can trigger hallucinations and other effects altering the mind, and are currently uncontrolled by the United Nations' 1961 Narcotic Drugs/1971 Psychotropic Substances...

This year marks the 50th anniversary of the United Nations Single Convention on Narcotic Drugs, signed on 30 March 1961. 73 countries were represented at the conference that took place in New York from 24 January to 25 March 1961, which sought to lay a new solid foundation for drug control in the post-war United Nations era. The aim was to replace the multiple existing multilateral treaties in ...

Neonatal thrombocytosis can result from maternal narcotic drug abuse. The case of a male infant is reported who was born to a woman with schizophrenia treated with non-narcotic psychotropic drugs during pregnancy; he developed severe prolonged thrombocytosis. The platelet count reached 1310 x 10(9)/l on day 15. This thrombocytosis persisted for three months. The patient was treated with dipyrid...

The largest group of new psychoactive substances is synthetic cannabinoids. Those that are placed on the list of controlled substances are immediately replaced by new uncontrolled ones. Significant and frequent changes on the “legal high” market often result in intoxications. The synthetic cannabinoid AB-CHMINACA was patented in 2009 and appeared on the European (narcotic) drug market in 2014. ...

  Background: Our institution’s traditional pain management strategy after shoulder arthroplasty has involved the utilization of postoperative patient-controlled narcotic analgesia. More recently, we have implemented a protocol (TLC) that utilizes a multimodal approach. The purpose of this study was to determine whether this change has improved pain control and decreased narcotic utilization. ...