نتایج جستجو برای: nanotoxicology
تعداد نتایج: 282 فیلتر نتایج به سال:
Precision-cut lung slices (PCLS) are an established ex vivo alternative to in vivo experiments in pharmacotoxicology. The aim of this study was to evaluate the potential of PCLS as a tool in nanotoxicology studies. Silver (Ag-NPs) and zinc oxide (ZnO-NPs) nanoparticles as well as quartz particles were used because these materials have been previously shown in several in vitro and in vivo studie...
For nanotoxicology investigations of air-borne particles to provide relevant results it is ever so important that the particle exposure of, for example cells, closely resembles the "real" exposure situation, that the dosimetry is well defined, and that the characteristics of the deposited nanoparticles are known in detail. By synthesizing the particles in the gas-phase and directly depositing t...
Faster, cheaper, sensitive, and mechanisms-based animal alternatives are needed to address the safety assessment needs of growing number nanomaterials (NM) their sophisticated property variants. Specifically, strategies that help identify prioritize alternative schemes involving individual test models, toxicity endpoints, assays for adverse outcomes, as well enable validation refinement these r...
Silver nanoparticles have been extensively researched and several applications such as antimicrobial anticancer, can be used in the agricultural, biomedical, pharmaceutical, textile area, among others, but its toxicity is still little understood. Nanoparticles measure between 1 – 100 nm most currently studied silver nanoparticle (AgNP). The main methods of synthesis are chemical biogenic pathwa...
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