Mouse polyoma virus major coat protein (VP1) expressed from a recombinant baculovirus is efficiently transported to infected cell nuclei and assembles into protein nanospheres morphologically similar to natural capsids. The nanospheres readily combine with plasmid DNA to form a hybrid gene therapy agent known as virus-like particles (VLPs). To facilitate large-scale production of VLPs free from...

The optical absorption for nanospheres made from Na, K, Al, Ag and Au are compared as a precursor to choosing the ideal metal for use in a negative permittivity (NP) near-field superlens. The relationship between optical absorption of the metal nanosphere and the ability of the NP lens to reconstruct the near-field is one to one. Metals with low dielectric losses have large plasmon absorption c...

The coupling between the spin and orbital degrees of freedom of photons is usually very weak, but recent studies have shown that this spin-orbit interaction (SOI) can be easily detected in metal structures. Here we show how the SOI of light is enhanced in plasmonic metal nanostructures, explore the underlying mechanism for this effect, and further demonstrate how it could potentially be harness...

Coupled plasmonic assemblies have recently attracted tremendous research interest in the field of Surface Enhanced Raman Scattering (SERS) due to their unique optical and biocompatible properties. Using DNA to connect different parts of assembled plasmonic nanostructures has been a simple but useful method to achieve the expected nanocomposites. This work prepared a satellite SERS substrate bas...

method for the analysis of 1,3-dihydroxy-2-methylxanthone (DHMXAN) in biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanosphere and nanocapsule formulations is developed and validated. The method does not require any complex sample extraction procedure. Chromatographic separation is made with a reversed-phase C18 column, using methanol–water (90:10, v/v) containing 1% (v/v) acetic acid as ...