نتایج جستجو برای: nanogel

تعداد نتایج: 448  

Journal: :Acta ophthalmologica 2016
Lisanne M Nibourg Edith Gelens Simone A F Nibourg Menno R de Jong Roel Kuijer Theo G van Kooten Steven A Koopmans

PURPOSE To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model. METHODS The lens content was removed, and the capsules were refilled with ...

2013
Deepa Bhagat Suman K. Samanta Santanu Bhattacharya

Environment-friendly management of fruit flies involving pheromones is useful in reducing the undesirable pest populations responsible for decreasing the yield and the crop quality. A nanogel has been prepared from a pheromone, methyl eugenol (ME) using a low-molecular mass gelator. This was very stable at open ambient conditions and slowed down the evaporation of pheromone significantly. This ...

Journal: :Nanomedicine: Nanotechnology, Biology and Medicine 2013

Journal: :Nano letters 2011
Todd Hoare Brian P Timko Jesus Santamaria Gerardo F Goya Silvia Irusta Samantha Lau Cristina F Stefanescu Debora Lin Robert Langer Daniel S Kohane

Drug delivery devices based on nanocomposite membranes containing thermoresponsive nanogels and superparamagnetic nanoparticles have been demonstrated to provide reversible, on-off drug release upon application (and removal) of an oscillating magnetic field. We show that the dose of drug delivered across the membrane can be tuned by engineering the phase transition temperature of the nanogel, t...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2017
Dandan Li Cornelus F van Nostrum Enrico Mastrobattista Tina Vermonden Wim E Hennink

Many biomolecules, such as proteins and genes, are presently used as therapeutics. However, their delivery to target sites inside cells is challenging because of their large molecular size, difficulties to pass cellular membranes and their susceptibility for enzymatic and chemical degradation. Nanogels, three-dimensional networks of hydrophilic polymers, are attractive carrier systems for these...

2014
Wujin Sun Tianyue Jiang Yue Lu Margaret Reiff Ran Mo Zhen Gu

A bioinspired cocoon-like anticancer drug delivery system consisting of a deoxyribonuclease (DNase)-degradable DNA nanoclew (NCl) embedded with an acid-responsive DNase I nanocapsule (NCa) was developed for targeted cancer treatment. The NCl was assembled from a long-chain single-stranded DNA synthesized by rolling-circle amplification (RCA). Multiple GC-pair sequences were integrated into the ...

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