نتایج جستجو برای: nano micelle
تعداد نتایج: 54312 فیلتر نتایج به سال:
Antimicrobial peptides are highly dynamic entities that acquire structure upon binding to a membrane interface. To better understand the structure and the mechanism for the molecular recognition of dodecylphosphocholine (DPC) micelles by the anticoccidial peptide PW2, we performed molecular dynamics (MD) simulations guided by NMR experimental data, focusing on strategies to explore the transien...
In this contribution, we report studies on the nature of binding of a potent antituberculosis drug, Rifampicin (RF) with a model drug delivery system, sodium dodecyl sulfate (SDS) micelle. Temperature dependent dynamic light scattering (DLS), conductometry, and circular dichroism (CD) spectroscopy have been employed to study the binding interaction of the drug with the micelle. The absorption s...
Many ionic liquids and low molecular weight polar solvents have been reported to support amphiphile self-assembly, with most of these reported for the first time in the last decade. This phenomenon is attributed to the solvophobic effect (analogous to the hydrophobic effect in water). However, to date there has been no systematic study which evaluates micelle formation in a large library of non...
Hyaluronan is a biopolymer suitable as a targeting unit in drug delivery systems according to affinity of hyaluronan to CD-44 receptor of cancer cells. We suppose that hyaluronan, when interacts with cationic surfactant, influences hydration of Stern layer of CTAB which affects fluorescence properties of 1-naphthol. We study excited state proton transfer of 1-naphthol in aqueous solution and in...
فرآیند ماشینکاری به روش تخلیه الکتریکی( edm)، یکی از فرآیندهای نوین ماشینکاری است که کاربردهای متنوعی در ساخت و تولید محصولات میکرومتری دارد. رشد و توسعه نانوتکنولوژی و نیاز به بهره گیری از روشهای جدید موجب شده است که جذبه زیادی برای استفاده از فرآیند edm در ساخت و تولید محصولات نانومتری ایجاد شود. فرآیند nano-edm یک فرآیند ماشینکاری حرارتی است که در آن از انرژی حرارتی حاصل از جرقه الکتریکی برا...
Amphotericin B (AmB) and Nystatin (Nys) are the drugs of choice for treatment of systemic and superficial mycotic infections, respectively, with their full clinical potential unrealized due to the lack of high therapeutic index formulations for their solubilized delivery. In the present study, using a coarse-grained (CG) molecular dynamics (MD) simulation approach, we investigated the interacti...
abstract this study is an attempt to determine the effect of nano- technology education on science lesson for fifth grade in primary school in the city of kermanshah. this research is experimental and is conducted in the from of pre-test and post- test for the control group. an achievement test was administered to determine the rate of learning in the students. the research is an applied one. ...
A filament stretching extensional rheometer and capillary breakup extensional rheometer are used to measure the extensional rheology of a series of wormlike micelle solutions experiencing a uniaxial elongational flow. The experiments are performed using a series of wormlike micelle solutions of both cetylpyridinium chloride and sodium salicylate NaSal in an aqueous sodium chloride solution and ...
در این مطالعه، فرمولاسیون¬های نانوی نور تخریب¬پذیر و زیست¬سازگار ایمیداکلوپرید و ایندوکساکارب، به واسطه¬ی کپسوله کردن مستقیم هر کدام ازآنها با کوپلیمرهای خطی- دندریتیک پلی¬سیتریک¬اسید-پلی¬اتیلن¬گلیکول-پلی¬سیتریک¬اسید (pca-peg-pca) تهیه شدند. سنتز این نانوآفت¬کش¬ها به دو صورت بدون کاربرد نانوذرات tio2 (nano-ind و nano-imi) و با کاربرد نانوذرات tio2 (nano-ind/tio2 و nano-imi/tio2) انجام شد. فرمول...
Micelle with mesomeric polyleucine (PDLLeu) core demonstrated the most uniform morphology, the smallest diameter and the highest drug loading capability compared to those with dextrorotatory (PDLeu), levorotatory (PLLeu) and racemic PLeu (PD/LLeu) cores. In addition, the modification with c(RGDfC) endowed the optimal PDLLeu micelle with enhanced intracellular drug release and cytotoxicity, indi...
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