BACKGROUND Polymer surface-modified inorganic nanoparticles (NPs) provide a multifunctional platform for assisting gene delivery. Rational structure design for enhancing colloidal stability and cellular uptake is an important strategy in the development of safe and highly efficient gene vectors. RESULTS Heterogeneous Au-coated Fe3O4 (Fe3O4@Au) NPs capped by polyethylene glycol-b-poly1-(3-amin...

A chemoselective route to induce Fe3O4@ZnO core-shell nanoparticles decorating carbon nanotubes to form MWCNT/Fe3O4@ZnO heterotrimers has been developed. Charges are redistributed in the heterotrimers through C-O-Zn, C-O-Fe and Fe-O-Zn bondings, giving rise to multiple electronic phases. The generated significant interfacial polarization and synergetic interaction between dielectric and magneti...

This paper reports on a novel and efficient β-glucosidase immobilization method using magnetic Fe3O4 nanoparticles as a carrier. Based on response surface methodology, the optimal immobilization conditions obtained were: glutaraldehyde (GA) concentration, 0.20%; enzyme concentration, 50.25 μg/mL; cross-linking time, 2.21 h; and the maximum activity recovery reached 89.35%. The magnetic immobili...

We descried a method to synthesize single crystalline Fe3O4 nanotubes by wet-etching the MgO inner cores of MgO/Fe3O4 core-shell nanowires. Homogeneous Fe3O4 nanotubes with controllable length, diameter, and wall thickness have been obtained. Resistivity of the Fe3O4 nanotubes was estimated to be approximately 4 x 10-2 Omega cm at room temperature. Magnetoresistance of approximately 1% was obse...

In gene therapy, how genetic therapeutics can be efficiently and safely delivered into target tissues/cells remains a major obstacle to overcome. To address this issue, nanoparticles consisting of non-covalently coupled polyethyleneimine (PEI) and folic acid (FA) to the magnetic and fluorescent core/shell of Fe3O4@SiO2(FITC) was tested for their ability to deliver Notch-1 shRNA. Our results sho...

The thermomagnetic behavior of remanence-induced magnetite (Fe3O4) particles in the pseudo-single-domain (PSD) size range (~0.1–10μm), which dominate the magnetic signature of many rock lithologies, is investigated using off-axis electron holography. Construction of magnetic induction maps allowed for the visualization of the vortex domain state in an individual Fe3O4 grain (~200 nm in diameter...

Columns packed with microsized titanium dioxide particles have been used effectively as precolumns for enriching phosphopeptides from complex mixtures. Nanosized titanium dioxide particles have a higher specific surface area and, hence, potentially higher trapping capacities toward phosphopeptides than do microsized particles. Thus, in this study, we employed TiO2-coated magnetic (Fe3O4/TiO2 co...

in order to study the effects of silver nano particles, magnetic field in corporation with barium, lithium and micronutrient fertilizers on wheat, an experiment was conducted at research farm of razavi research and technology institute in 2008. experiment carried out with eigth treatments based on randomized complete block design with four replications. treatments were including (t1) magnetic f...

one-pot reaction of aldehydes or ketons with aniline derivatives was performed using nabh4 and fe3o4 magnetic nanoparticles (mnps). the optimum amount of fe3o4 mnps was 5 mol% under solvent free condition. the corresponding products were obtained in good to excellent yields. the magnetically recoverable iron oxide nanoparticles are found to be efficient for synthesis of amine derivatives. these...

BACKGROUND Both thermotherapy and arsenic have been shown to be active against a broad spectrum of cancers. To reduce the limitations of conventional thermotherapy, improve therapeutic anticancer activity, reduce the toxicity of arsenic on normal tissue, and increase tissue-specific delivery, we prepared a nanosized As2O3/Fe3O4 complex (Fe3O4 magnetic nanoparticles encapsulated in As2O3). We as...