Multiphasic calcium phosphate powders were synthesized by the acidic route, using lactic acid as a chelating agent that allows production of stable and rich solution ions at room temperature. After pH adjusting, without varying concentrations precursor solution, XRD FTIR analyses showed different CaP phases before after heat treatment 1000 °C. At 5, brushite plate-like particles produced, while...

A bone scaffold material (nano-HA/ collagen/PLA composite) was developed by biomimetic synthesis. It shows some features of natural bone both in main composition and hierarchical microstructure. Nano-hydroxyapatite and collagen assembled into mineralized fibril. The three-dimensional porous scaffold materials mimic the microstructure of cancellous bone. Cell culture and animal model tests showe...

The elastic properties of dentin, a biological composite consisting of stiff hydroxyapatite (HAP) nano-platelets within a compliant collagen matrix, are determined by the volume fraction of these two phases and the load transfer between them. We have measured the elastic strains in situ within the HAP phase of bovine dentine by high energy X-ray diffraction for a series of static compressive st...

Abstract Stress shielding is known to cause bone refracture or low healing rate in fractured bones. The numerical study of process a transverse tibia was conducted this research reduce the stress shielding. and strain on callus were evaluated when plates different metallic non-metallic biomaterials used. Time varying material properties applied, loading conditions coupled with callus. distribut...

Objective This study aimed to investigate the damage mechanism of nanosized hydroxyapatite (nano-HAp) on mouse aortic smooth muscle cells (MOVASs) and the injury-inhibiting effects of diethyl citrate (Et2Cit) and sodium citrate (Na3Cit) to develop new drugs that can simultaneously induce anticoagulation and inhibit vascular calcification. Methods The change in cell viability was evaluated usi...

STATEMENT OF THE PROBLEM The adhesion of resin-modified glass-ionomer (RMGI) to composite resin has a very important role in the durability of sandwich restorations. Hydroxyapatite is an excellent candidate as a filler material for improving the mechanical properties of glass ionomer cement. PURPOSE The aim of this study was to assess the effect of adding micro- and nano-hydroxyapatite (HA) p...

In this work, we report the effect of biopolymers (starch and gelatin) on in vitro biocompatibility property of nano hydroxyapatite (nHAp) composites. Cell culture and MTT assays were performed for in vitro biocompatibility. They show that nHAp can affect the proliferation of cells and the nHAp-starch and nHAP-gelatin biocomposites have no negative effect on the cell morphology, viability and p...

Hydroxyapatite (HAp) forms the main mineral component of bone and teeth. This naturally occurring HAp is in the form of nano-metre sized crystallites of Ca10(PO4)6(OH)2 that contain a number of cation and anion impurities, for example CO3 , F, Na, Mg and Sr. Synthetic nano-sized HAp particles exhibit favourable biocompatibility and bioactivity and in order to better match the composition to nat...

Cancerous diseases and resulting from bacteria fungi are some of the pressures that humans face. Therefore, development biomaterials resistant to cancerous diseases, bacteria, has become one requirements medical field extend life biomaterial fight pathogens after implanting these materials inside human body. One important used in orthopedics is hydroxyapatite. In this research, Nano substituted...

Despite the merits of glass ionomer cements (GICs), they suffer from weak mechanical properties such as low wear resistance. In this study, the mechanical properties of GICs after incorporating chitosan and nano-hydroxyapatite was investigated. The samples were prepared in four groups, including non-modified GIGs (NMGIC, n = 5), chitosan incorporated GICs (CHGIC, n = 5), nano-hydroxyapatite inc...