ABSTRACT Advances in Nuclear Magnetic Resonance (NMR) spectroscopy is a cornerstone structure elucidation of polycyclic 'cage' scaffolds. Due to the compactness these compounds, much overlap, as well unique through-space and bond NMR interactions are frequently observed. This review serves guide for future derivatives by providing some typical relevant aspects characteristic trends, substituent...

We present a descriptive model of choice derived from neuroscientific models efficient value representation in the brain. Our basic model, special case Expected Utility Theory, can capture number behaviors predicted by Prospect Theory. It achieves this with only two parameters: time-indexed “payoff expectation” (reference point) and free parameter we call “predisposition”. A simple extension ou...

First expressed by Allais in the early fifties, dissatisfaction with the expected utility model of individual risk taking behavior has mushroomed in recent years, as the number of papers in this volume, its predecessor (Allais & Hagen(l979», and elsewhere2 indicates. The nature of the current debate, i.e. whether to reject a theoretically elegant and heretofore tremendously useful descriptive m...