Age-related cataract is clinically and genetically heterogeneous disorder affecting the ocular lens, and the leading cause of vision loss and blindness worldwide. Here we screened nonsynonymous single nucleotide polymorphisms (nsSNPs) of a novel gene, EPHA2 responsible for age related cataracts. The SNPs were retrieved from dbSNP. Using I-Mutant, protein stability change was calculated. The pot...

We describe a spectroelectrochemical approach to accelerated electrochemical stability studies of conjugated polymers under oxidative stress. The polaron stabilities of alternating copolymers based on (i) thiophene and thiazole, namely PTTz, and (ii) bithiophene and thiazole, namely PTTTz, are compared in neat films with that of P3HT. P3HT is found to be the most stable whilst PTTz is found to ...

In this paper we overview the integration of a framework that generically manages the system resources in the form of contracts, namely the FRESCOR framework, with a flexible network resource. We describe how a network resource, namely FTT-SE, supports the FRESCOR framework services and, likewise, how the network services are made available to the application through the contracting framework.

This paper describes the error correction model that we used for the Automatic Correction of Arabic Text shared task. We employed two correction models, namely a character-level model and a casespecific model, and two punctuation recovery models, namely a simple statistical model and a CRF model. Our results on the development set suggest that using a cascaded correction model yields the best r...

Several newer isosteric analogues of glycosyl phosphates, namely of glycosyl phosphoramidates, were synthesized in good yields using Staudinger reaction of their corresponding azides with trimethyl phosphite followed by de-O-acetylation. The structure and conformation of the fully protected analogue synthesized, namely 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl bismethoxyphosphoramidate, was ...

in this paper, nonlinear klein-gordon equation with quadratic term is solved by means of an analytic technique, namely the homotopy analysis method (ham).comparisons are made between the adomian decomposition method (adm), the exact solution and homotopy analysis method. the results reveal that the proposed method is very effective and simple.

representation and modeling of economic uncertainty is addressed by different modeling methods, namely stochastic variables and probabilities, interval analysis, and fuzzy numbers, in particular triple estimates. fo-cusing on discounted cash flow analysis numerical results are presented, comparisons are made between alter-native modeling methods, and characteristics of the methods are discussed.

Three new plant growth regulatory sesquiterpenoids were isolated from the Lactarius repraesentaneus fungus. Their structures were elucidated to be a protoilludene sesquiterpene, namely repraesentin A (1), and two related sesquiterpenes, namely repraesentins B (2) and C (3). Compounds 1-3 showed promotion activities toward the radicle elongation of lettuce seedlings by 136%, 118% and 184% at 67 ...

In this paper, we derive rigorously a classical simpliied model of ocean circulation , namely the so called homogeneous model of wind driven ocean circulation (see the monograph of J. Pedlosky 19]) and two of its possible boundary layer behavior, namely Munk layers and Stommel layers.

Four compounds that belong to two structure types, namely dibenzylbutyrolactone and sesterterpenoids, were obtained from the extract of the strain Aspergillus sp. (2P-22), isolated from a marine sponge, Cliona chilensis. Among them, compound 1 was identified as new, namely butylrolactone-VI. The structures of these compounds were characterized on the basis of spectroscopic data. Biological acti...