Transcranial direct current stimulation (tDCS) modulates cortical neural activity and hemodynamics. Electrophysiological methods (electroencephalography-EEG) measure neural activity while optical methods (near-infrared spectroscopy-NIRS) measure hemodynamics coupled through neurovascular coupling (NVC). Assessment of NVC requires development of NIRS-EEG joint-imaging sensor montages that are se...

The mechanisms underlying endothelial cell injury and defective vascular repair in systemic sclerosis (SSc) remain unclear. Since the recently discovered angiogenic T cells (Tang) may have an important role in the repair of damaged endothelium, this study aimed to analyze the Tang population in relation to disease-related peripheral vascular features in SSc patients. Tang (CD3+CD31+CXCR4+) were...

The association between neural activity and cerebral blood flow (CBF) has been used to assess neurovascular coupling (NVC) in health and diseases states, but little attention has been given to the contribution of simultaneous changes in peripheral covariates. We used an innovative approach to assess the contributions of arterial blood pressure (BP), PaCO2, and the stimulus itself to changes in ...

Macrosurfactants consisting of water-soluble poly(vinylcaprolactam) (PVCap) or poly(vinylpyrrolidone) (PVP) segments with comparatively shorter hydrophobic poly(styrene) (PS) poly(2,3,4,5,6-pentafluorostyrene) (PPFS) were used as kinetic hydrate inhibitors (KHIs). These synthesized 2-cyanopropan-2-yl N-methyl-N-(pyridin-4-yl)dithiocarbamate switchable reversible addition–fragmentation chain tra...

BACKGROUND Acute stroke is known to impair cerebral blood flow (CBF) regulation, but the longitudinal changes of these effects have been poorly reported. The main CBF regulatory mechanisms [cerebral autoregulation (CA) and neurovascular coupling (NVC)] were assessed over 3 months after acute ischaemic stroke. METHODS Recordings of CBF velocity (CBFv), blood pressure (BP), and end-tidal CO2 we...

Sustainable forest production requires an understanding of the effects of site disturbance on tree growth and the consequences of soil amelioration and vegetation control practices. We assessed the impacts of biomass removals at harvest, soil compaction and tillage, and vegetation control on early growth of Douglas-fir in coastal Washington. Harvest treatments included removal of commercial bol...

BACKGROUND Bladder dysfunction induced by spinal cord injury (SCI) can become problematic and severely impair the quality of life. Preclinical studies of spinal cord injury have largely focused on the recovery of limb function while neglecting to investigate bladder recovery. OBJECTIVE The present study was performed to investigate and review the effect of stem cell-based cell therapy on blad...

Background Both cardiovascular and complement-mediated disorders might lead to microvascular damage in anti-neutrophil cytoplasm autoantibodies (ANCA)-associated vasculitides (AAV). No evidence of subclinical retinal abnormalities neither their potential correlation with capillaroscopy anomalies has been reported eosinophilic granulomatosis polyangiitis (EGPA), (GPA), microscopic (MPA). Objecti...