نتایج جستجو برای: n cyclohexyl 2
تعداد نتایج: 3133276 فیلتر نتایج به سال:
Abstract N-Substituted phenyl/cyclohexyl-2-(pyridine-4-carbonyl) hydrazine-1-carbothioamides (2a–r) were synthesized, characterized by spectral and analytical data. The compounds evaluated for antibacterial activity the disc diffusion method. Most of showed against Gram-positive bacteria. Compound 2h with 4-Sulfapyrimidine phenyl substitution was found to be most promising candidate, active met...
A new series of 4-aminoquinoline Mannich base derivatives were prepared by selectively modifying the aliphatic diethyl amino function of isoquinewith different aliphatic/aromatic heterocyclic primary amino moieties at Mannich side chain. The synthesized compounds were characterized by their physical,analytical and spectral data, and screened for in vitro antimalarial activity against a chloroqu...
Thirty-seven arylcyclohexylamines including phencyclidine (PCP) and derivatives, N[1-(2-thienyl)cyclohexyl]piperidine (TCP) and derivatives and N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine (BTCP) were assessed for their ability to inhibit [3H]PCP binding and [3H]dopamine ([3H]DA) synaptosomal uptake. Their pharmacological property (ataxia) was measured by means of the rotarod test. A very g...
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