This study was conducted to identify changes in genomic and proteomic skin profiles of 40 patients with AD lesions treated crisa, a nonsteroidal PDE4 inhibitor, vehicle compare them those nonlesional (NL) normal (N) skin. 2 randomly assigned (1:1 intrapatient manner) target were crisa or BID for 14 days. Punch biopsies collected from lesional 20 healthy controls at baseline days 8/15 treatment....

Introduction. Stroke can be a complication and/or presenting sign of COVID-19 infection. Although there is growing evidence on stroke in infection, only few these studies were done Asia and very scarce the local setting. Objective. This study aimed to characterize clinical profile, management, functional outcome patients with acute Methods. was single-center retrospective from March 30 October ...

BACKGROUND Although the incidence of ventricular tachyarrhythmias associated with structural heart disease is highest in winter and during the daytime, seasonal and circadian variations among cardiac events in patients with congenital long QT syndrome (LQTS) remain unknown. The present study aims to determine seasonal and circadian cardiac events in patients with a congenital LQTS genotype. M...

We show that a point set of cardinality n in the plane cannot be the vertex set of more than 59 O(n−6) straight-edge triangulations of its convex hull. This improves the previous upper bound of 276.75n+O(log(n)).

OBJECTIVE To evaluate physical growth, development and nutritional status in adults with previously undiagnosed/ untreated phenylketonuria (PKU). METHODS Four hundred adults (201 females and 199 males) with severe intellectual disability who were born prior to compulsory neonatal screening (before 1976) and who resided in social welfare homes in southeastern Poland were screened for PKU. The ...

The purpose of this study was to determine the interest class X students in learning art and culture at SMA N 1 Bengkulu Selatan. This type research is quantitative described by descriptive statistics. population were Selatan sample studied IPS 3. instrument a questionnaire (questionnaire). Data collection techniques carried out distributing questionnaires, processing returning questionnaires. ...

BACKGROUND Despite improvements in surgical techniques, urinary incontinence (UI) is not uncommon after radical prostatectomy (RP), and it may dramatically worsen quality of life (QoL). OBJECTIVE To determine the benefit of starting pelvic floor muscle exercise (PFME) 30d before RP and of continuing PFME postoperatively for early recovery of continence. DESIGN, SETTING, AND PARTICIPANTS A r...

The mechanism whereby fragments of streptokinase (SK) derived from its N terminus (e.g., SK1-59 or SK1-63) enhance the low plasminogen (PG)-activating ability of other fragments, namely SK64-386, SK60-414, SK60-387, and SK60-333 (reported previously), has been investigated using a synthetic peptide approach. The addition of either natural SK1-59, or chemically synthesized SK16-59, at saturation...